Putting bacteria on the cancer map
- PMID: 36630910
- DOI: 10.1016/j.immuni.2022.12.016
Putting bacteria on the cancer map
Abstract
In a study recently in Nature, Galeano Niño et al. use spatial profiling and single-cell RNA sequencing to delineate the spatial organization of microbiota in cancer. Their findings demonstrate that tumor-associated microbiota coalesce in micro-niches where they may mediate immune and epithelial oncogenic roles.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer.Nature. 2022 Nov;611(7937):810-817. doi: 10.1038/s41586-022-05435-0. Epub 2022 Nov 16. Nature. 2022. PMID: 36385528 Free PMC article.
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