Targets mapped for almost all human kinase enzymes

Comment

Sean J Humphrey et al. Nature. 2023 Jan.

. 2023 Jan;613(7945):637-638.

doi: 10.1038/d41586-022-04583-7.

No abstract available

Keywords: Cell biology.

Comment on

An atlas of substrate specificities for the human serine/threonine kinome.
Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, van Vlimmeren AE, Andrée-Busch N, Käufer NF, Dorovkov MV, Ryazanov AG, Takagi Y, Kastenhuber ER, Goncalves MD, Hopkins BD, Elemento O, Taatjes DJ, Maucuer A, Yamashita A, Degterev A, Uduman M, Lu J, Landry SD, Zhang B, Cossentino I, Linding R, Blenis J, Hornbeck PV, Turk BE, Yaffe MB, Cantley LC. Johnson JL, et al. Nature. 2023 Jan;613(7945):759-766. doi: 10.1038/s41586-022-05575-3. Epub 2023 Jan 11. Nature. 2023. PMID: 36631611 Free PMC article.

1. Cohen, P. Nature Rev. Drug Discov. 1, 309–315 (2002). - PubMed - DOI
1. Attwood, M. M., Fabbro, D., Sokolov, A. V., Knapp, S. & Schiöth, H. B. Nature Rev. Drug Discov. 20, 839–861 (2021). - PubMed - DOI
1. Needham, E. J., Parker, B. L., Burykin, T., James, D. E. & Humphrey, S. J. Sci. Signal. 12, eaau8645 (2019). - PubMed - DOI
1. Johnson, J. L. et al. Nature 613, 759–766 (2023).
1. Humphrey, S. J., James, D. E. & Mann, M. Trends Endocrinol. Metab. 26, 676–687 (2015). - PubMed - DOI