Could the control of O-GlcNAcylation play a key role in cardiac remodeling?
- PMID: 36635529
- DOI: 10.1038/s41440-023-01171-8
Could the control of O-GlcNAcylation play a key role in cardiac remodeling?
Keywords: Cardiac remodeling; Intermittent hypoxia; O-GlcNAcylation.
Comment on
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Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice.Hypertens Res. 2019 Dec;42(12):1858-1871. doi: 10.1038/s41440-019-0311-x. Epub 2019 Aug 13. Hypertens Res. 2019. PMID: 31409917
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Augmented O-GlcNAcylation exacerbates right ventricular dysfunction and remodeling via enhancement of hypertrophy, mitophagy, and fibrosis in mice exposed to long-term intermittent hypoxia.Hypertens Res. 2023 Mar;46(3):667-678. doi: 10.1038/s41440-022-01088-8. Epub 2022 Nov 14. Hypertens Res. 2023. PMID: 36376492
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