An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before
sharing sensitive information, make sure you’re on a federal
government site.
The site is secure.
The https:// ensures that you are connecting to the
official website and that any information you provide is encrypted
and transmitted securely.
1 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Brigham & Women's Hospital, Boston, MA, USA. zwalker1@bwh.harvard.edu.
2 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Brigham & Women's Hospital, Boston, MA, USA.
1 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Brigham & Women's Hospital, Boston, MA, USA. zwalker1@bwh.harvard.edu.
2 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Brigham & Women's Hospital, Boston, MA, USA.
The use of preimplantation genetic testing for aneuploidy (PGT-A) in poor responders undergoing assisted reproductive technology has been a topic of debate with controversial results. It is critical to note the denominators used in data presented. Herein, we comment on the results found in the study by Kahraman et al. on the utility of PGT-A in poor responders with a single, good-quality blastocyst.
Kahraman S, Duzguner INB, Sahin Y, Irez T. What to advise to patients with only one good quality blastocyst, PGT-A or not? Outcomes of 2064 cycles. J Assist Reprod Genet. 2022;39(11):2555–2562. 10.1007/S10815-022-02617-7.
-
PMC
-
PubMed
Gordon CE, Keefe KW, Ginsburg ES, Racowsky C, Lanes A. Embryo attrition in planned PGT-A: predicting the number of available blastocysts for transfer. J Assist Reprod Genet. 2022;39(1):173–181. doi: 10.1007/S10815-021-02365-0.
-
DOI
-
PMC
-
PubMed
Morin SJ, Kaser DJ, Franasiak JM. The dilemma of aneuploidy screening on low responders. Curr Opin Obstet Gynecol. 2018;30(3):179–184. doi: 10.1097/GCO.0000000000000449.
-
DOI
-
PubMed
Takeda E, Sugiura-Ogasawara M, Ebara T, et al. Attitudes toward preimplantation genetic testing for aneuploidy among patients with recurrent pregnancy loss in Japan. J Obstet Gynaecol Res. 2020;46(4):567–574. doi: 10.1111/JOG.14212.
-
DOI
-
PubMed
Deng J, Hong HY, Zhao Q, et al. Preimplantation genetic testing for aneuploidy in poor ovarian responders with four or fewer oocytes retrieved. J Assist Reprod Genet. 2020;37(5):1147–1154. doi: 10.1007/S10815-020-01765-Y.
-
DOI
-
PMC
-
PubMed