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. 2023 Feb 1;42(2):122-124.
doi: 10.1097/INF.0000000000003766. Epub 2022 Nov 7.

Decreasing Incidence of the Multisystem Inflammatory Syndrome in Children Over 3 Pandemic Waves

Irini Eleftheriou  1 , Despina Maritsi  1 , Stavroula Lampidi  1 , Konstantina Charisi  2 , Petrina Vantsi  2 , Kleopatra Skourti  3 , Filippos Filippatos  3 , Ioannis Amplianitis  4 , Despina Dimou  5 , Kyriaki Papadopoulou-Legbelou  6 , Efimia Papadopoulou-Alataki  6 , Parthena Kampouridou  7 , Patra Koletsi  5 , Lampros Fotis  8 , Elena Vergadi  9 , Despoina Gkentzi  4 , Evangelia Farmaki  10 , Vassiliki Papaevangelou  8 , Emmanouil Galanakis  9 , Ioanna N Grivea  11 , George A Syrogiannopoulos  11 , Vana Spoulou  3 , Nikos Spyridis  1 , Athanasios Michos  3 , Emmanuel Roilides  2 , Maria N Tsolia  1
Affiliations

Decreasing Incidence of the Multisystem Inflammatory Syndrome in Children Over 3 Pandemic Waves

Irini Eleftheriou et al. Pediatr Infect Dis J. .

Abstract

In this nationwide retrospective study, a substantial decline in the incidence of multisystem inflammatory syndrome in children over 3 successive pandemic waves characterized by different severe acute respiratory syndrome coronavirus 2 variants was documented-from 3.4 of 1000 to 1.1 of 1000 and finally to 0.25 of 1000 confirmed severe acute respiratory syndrome coronavirus 2 positive cases (P < 0.0001), respectively, whereas clinical findings and severity did not significantly vary.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

References

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Supplementary concepts