Mechanical Mitral Valves and INR: How Low Can You Go?

Affiliations

¹ Division of Cardiac Surgery, Department of Surgery, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
² Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
³ Division of Cardiac Surgery, Department of Surgery, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, H4 05, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5. Electronic address: stephen.fremes@sunnybrook.ca.

Comment

Kevin R An et al. Ann Thorac Surg. 2023 Apr.

. 2023 Apr;115(4):938-939.

doi: 10.1016/j.athoracsur.2023.01.008. Epub 2023 Jan 12.

¹ Division of Cardiac Surgery, Department of Surgery, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
² Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
³ Division of Cardiac Surgery, Department of Surgery, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, H4 05, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5. Electronic address: stephen.fremes@sunnybrook.ca.

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Low-Dose vs Standard Warfarin After Mechanical Mitral Valve Replacement: A Randomized Trial.
Chu MWA, Ruel M, Graeve A, Gerdisch MW, Damiano RJ Jr, Smith RL 2nd, Keeling WB, Wait MA, Hagberg RC, Quinn RD, Sethi GK, Floridia R, Barreiro CJ, Pruitt AL, Accola KD, Dagenais F, Markowitz AH, Ye J, Sekela ME, Tsuda RY, Duncan DA, Swistel DG, Harville LE 3rd, DeRose JJ, Lehr EJ, Alexander JH, Puskas JD; PROACT Mitral Investigators. Chu MWA, et al. Ann Thorac Surg. 2023 Apr;115(4):929-938. doi: 10.1016/j.athoracsur.2022.12.031. Epub 2023 Jan 4. Ann Thorac Surg. 2023. PMID: 36610532 Clinical Trial.