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. 2022 Dec 8:87:e661-e667.
doi: 10.5114/pjr.2022.123563. eCollection 2022.

The role of contrast-enhanced ultrasound in the evaluation of hepatobiliary lesions and its correlation with pathological findings

Krishan Kumar  1 , Sandeep Kaur  1 , Rupinderjeet Kaur  2 , Taranjeet Kaur  3 , Paramdeep Singh  1
Affiliations

The role of contrast-enhanced ultrasound in the evaluation of hepatobiliary lesions and its correlation with pathological findings

Krishan Kumar et al. Pol J Radiol. .

Abstract

Purpose: To evaluate the efficacy of contrast-enhanced ultrasound (CEUS) in assessing hepatobiliary lesions, and to correlate the findings of CEUS for hepatobiliary lesions with those of pathological examination performed through fine needle aspiration.

Material and methods: This prospective observational study included 50 patients with hepatobiliary lesions, who were referred for CEUS. The findings of CEUS were correlated with pathological findings.

Results: CEUS was determined to be a highly sensitive and specific imaging modality for the detection and characterization of hepatobiliary lesions, with the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of CEUS being 100.0%, 96.8%, 66.7%, 100.0%, and 96.7%, respectively, when correlated with pathological findings.

Conclusions: CEUS is a highly sensitive and specific imaging modality for the detection and characterization of hepatobiliary lesions, with wide availability in the present scenario.

Keywords: SOL; contrast; liver; pathology; ultrasound.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
50-year-old male, a known case of colonic adenocarcinoma presented with pain right hypochondrium for the last one month. A) B-mode conventional ultrasound image shows hyperechoic mass in liver (arrow). B-C) Ultrasound images obtained after contrast medium administration show nodules which are to be hypoechoic (arrows) in comparison with surrounding liver parenchyma in portal and late phases – hypovascular metastasis. D) Histopathology confirmed the diagnosis of liver metastasis
Figure 2
Figure 2
55-year-male, a known case of hepatitis-C presented with history of weight loss. A) B-mode conventional ultrasound image shows hypoechoic mass in left lobe (arrow) of liver. B-C) Ultrasound images obtained after contrast medium administration shows an eccentric nodule to be hypervascular (arrow) in arterial phase (B) and portal phase (C) with washout in delayed phases that was suggestive of hepatocellular carcinoma. D) The diagnosis was confirmed by histopathology
Figure 3
Figure 3
60-year-old female with history of weight loss and heaviness in right hypochondrium. A) Baseline ultrasound illustrates an ill-defined heterogeneous mass (arrow) at the porta hepatis. B) Contrast-enhanced ultrasound (CEUS) after 25 s after microbubble contrast administration demonstrates mild enhancement (arrow). C) CEUS at 80 s after microbubble contrast administration demonstrates hypoenhancement (arrow) within the lesion. D) On histopathological correlation, diagnosis of intrahepatic cholagiocarcinoma was confirmed
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