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. 2023 Jan;18(1):451-452.
doi: 10.1016/j.jds.2022.09.012. Epub 2022 Sep 30.

Oral granulomatosis with polyangiitis

Chen-Hsi Tsai  1 , Yuk-Kwan Chen  2   3   4 , Yu Feng Chen  1 , Chih-Huang Tseng  3   4
Affiliations

Oral granulomatosis with polyangiitis

Chen-Hsi Tsai et al. J Dent Sci. 2023 Jan.
No abstract available

Keywords: Granulomatosis with polyangiitis; Oral.

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Conflict of interest statement

The authors have no conflicts of interest relevant to this article.

Figures

Fig. 1
Figure 1
Clinical, radiographic, and microscopic photographs of the current case of GPA with oral involvement. Hyperplastic, hemorrhagic friable gingiva was present at labial gingiva of tooth 13 to 23 (A). Multiple ulcerative granulomatous lesions were identified at pan-oral buccal and lingual gingivae (B and C). The periapical radiographs of upper anterior teeth revealed moderate horizontal bony destruction of the alveolar process (D). The histopathological examination showed an ill-defined, necrotizing granulomatous lesion with papillary surface. The covering epithelium displayed pseudoepitheliomatous hyperplasia (E). Numerous multinucleated giant cells (arrow) were present in the granulation tissue (F). Proliferation of vascular channels and a heavy inflammatory infiltrate consisting of neutrophils and lymphocytes (G). (Hematoxylin and eosin stain; original magnification; E, 10×; F and G, 40 × ).
See this image and copyright information in PMC

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