Defining conversion therapy for esophageal squamous cell carcinoma
- PMID: 36643357
- PMCID: PMC9831898
- DOI: 10.1002/ags3.12623
Defining conversion therapy for esophageal squamous cell carcinoma
Abstract
A multimodality treatment conference with experts from across East Asia was held to establish a consensus for conversion therapy. An agreement was reached that conversion therapy was defined as surgery or chemoradiotherapy (CRT) aiming at cure after initial treatment for tumors that were initially unresectable due to adjacent organ invasion or distant metastasis.
Keywords: conversion surgery; conversion therapy; esophageal squamous cell carcinoma.
© 2022 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterological Surgery.
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References
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- Sun JM, Shen L, Shah MA, Enzinger P, Adenis A, Doi T, et al. Pembrolizumab plus chemotherapy versus chemotherapy alone for first‐line treatment of advanced oesophageal cancer (KEYNOTE‐590): a randomised, placebo‐controlled, phase 3 study. Lancet. 2021;398(10302):759–71. - PubMed
-
- Doki Y, Ajani JA, Kato K, Xu J, Wyrwicz L, Motoyama S, et al. Nivolumab combination therapy in advanced esophageal squamous‐cell carcinoma. N Engl J Med. 2022;386(5):449–62. - PubMed
-
- Al‐Batran SE, Homann N, Pauligk C, Illerhaus G, Martens UM, Stoehlmacher J, et al. Effect of neoadjuvant chemotherapy followed by surgical resection on survival in patients with limited metastatic gastric or gastroesophageal junction cancer: the AIO‐FLOT3 trial. JAMA Oncol. 2017;3(9):1237–44. - PMC - PubMed
-
- Terada M, Hara H, Daiko H, Mizusawa J, Kadota T, Hori K, et al. Phase III study of tri‐modality combination therapy with induction docetaxel plus cisplatin and 5‐fluorouracil versus definitive chemoradiotherapy for locally advanced unresectable squamous‐cell carcinoma of the thoracic esophagus (JCOG1510: TRIANgLE). Jpn J Clin Oncol. 2019;49(11):1055–60. - PubMed
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