Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Sep 29;8(1):202-205.
doi: 10.1016/j.ekir.2022.09.020. eCollection 2023 Jan.

Subclass Changes in Fibrillary Glomerulonephritis

Affiliations
Case Reports

Subclass Changes in Fibrillary Glomerulonephritis

Laura E Biederman et al. Kidney Int Rep. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Patient 2- Initial biopsy in 2012 with strong staining for IgG1 (a), weak staining for IgG2 (b), negative IgG3 (c), and strong staining for IgG4 (d) on immunofluorescence. Glomeruli are enlarged with an expanded mesangium on PAS stain (e). Electron microscopy shows classic fibrils (f). Subsequent biopsy in 2022 with strong staining for IgG1 (g), no significant staining for IgG2, IgG3, and IgG4 (h, i, and j, respectively). Glomeruli show further enlargement with increased mesangial expansion of PAS stain (k). Electron microscopy shows classic fibrils (l).

References

    1. Alpers C.E., Kowalewska J. Fibrillary glomerulonephritis and immunotactoid glomerulopathy. Journal of the American Society of Nephrology. 2008;19:34–37. doi: 10.1681/ASN.2007070757. - DOI - PubMed
    1. Javaugue V., Karras A., Glowacki F., et al. Long-term kidney disease outcomes in fibrillary glomerulonephritis: A case series of 27 patients. Am J Kidney Dis. 2013;62:679–690. doi: 10.1053/j.ajkd.2013.03.031. - DOI - PubMed
    1. Hemminger J., Nadasdy G., Satoskar A., Brodsky S.V., Nadasdy T. IgG Subclass Staining in Routine Renal Biopsy Material. Am J Surg Pathol. 2016;40:617–626. doi: 10.1097/PAS.0000000000000605. - DOI - PubMed
    1. Rosenstock J.L., Markowitz G.S., Valeri A.M., Sacchi G., Apple G.B., D’Agati V.D. Fibrillary and immunotactoid glomerulonephritis: distinct entities with different clinical and pathologic features. Kidney Int. 2003;63:1450–1461. doi: 10.1046/J.1523-1755.2003.00853.X. - DOI - PubMed
    1. Bridoux F., Hugue V., Coldefy O., et al. Fibrillary glomerulonephritis and immunotactoid (microtubular) glomerulopathy are associated with distinct immunologic features. Kidney Int. 2002;62:1764–1775. doi: 10.1046/J.1523-1755.2002.00628.X. - DOI - PubMed

Publication types

LinkOut - more resources