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. 2023 Mar;28(3):187-195.
doi: 10.1111/nep.14143. Epub 2023 Jan 27.

Risk factors for loss to follow-up and outcomes after kidney donation in New Caledonian living donors

Noémie Baroux  1 , David De Saint Gilles  2 , Thomas Lamy  2 , Véronique Biche  2 , Kate Wyburn  3 , Nicolas Quirin  1   2
Affiliations

Risk factors for loss to follow-up and outcomes after kidney donation in New Caledonian living donors

Noémie Baroux et al. Nephrology (Carlton). 2023 Mar.

Abstract

Aim: For patients with end-stage kidney disease, living-donor kidney transplantation is the best therapy. There is a duty to ensure that the donor is followed-up after donation on a regular and long-term basis. Conditions may arise, such as hypertension, chronic kidney disease, metabolic conditions, and these should be identified and treated as soon as possible for the donor's own longer term wellbeing. In this retrospective cohort study, we investigated the risk of loss to follow-up after kidney donation for living donors.

Methods: Data were collected from the unique Caledonian nephrology medical record software and a phone survey. We evaluated the association between being lost to follow up and donor recipient relationship, donor socio-demographic characteristics, donation characteristics and care access. We performed a multivariate analysis to identify risk factors of loss to follow-up.

Results: Among the the 86 donors included, 38 (44%) had no nephrology consultation for more than 16 months. The rate of donor follow up decreased from 81% at 2 years to 49% at 10 years after donation. In the multivariate analysis, age less than 45 years old at donation increased the risk of loss to follow up to 4.5 (95% CI 2.0-10.3) and not being a spouse increased the risk to 3.9 (95% CI 1.5-11.1).

Conclusion: To conclude, efforts should be made to improve the rate at which donors are followed up in New Caledonia with special attention to younger donors and donors without a marital link with the recipient.

Keywords: end-stage kidney disease; follow up; living donor transplantation; living kidney donors; pacific islands; transplantation.

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References

REFERENCES

    1. Poggio ED, Augustine JJ, Arrigain S, Brennan DC, Schold JD. Long-term kidney transplant graft survival-making progress when most needed. Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg. 2021;21:2824-2832. doi:10.1111/ajt.16463
    1. Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999;341:1725-1730. doi:10.1056/NEJM199912023412303
    1. Landreneau K, Lee K, Landreneau MD. Quality of life in patients undergoing hemodialysis and renal transplantation-a meta-analytic review. Nephrol Nurs J J Am Nephrol Nurses Assoc. 2010;37:37-44.
    1. Rosenberg ME. Presidential address kidney week 2019: winning the war on kidney diseases: the time is now. Clin J Am Soc Nephrol CJASN. 2020;15:1213-1219. doi:10.2215/CJN.15011219
    1. Girlanda R. Deceased organ donation for transplantation: challenges and opportunities. World J Transplant. 2016;6:451-459. doi:10.5500/wjt.v6.i3.451

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