Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Apr;36(3):627-630.
doi: 10.1007/s40620-022-01538-z. Epub 2023 Jan 16.

Salt-losing tubulopathy worsening the prognosis of renal sarcoidosis

Affiliations

Salt-losing tubulopathy worsening the prognosis of renal sarcoidosis

Anis Abu Ayyach et al. J Nephrol. 2023 Apr.
No abstract available

Keywords: Bartter-like syndrome; Renal sarcoidosis; Salt-losing tubulopathy; Systemic sarcoidosis.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Time course of Scr, eGFR from 2006 to 2012 using the MDRD equation, and from 2012 to 2020 using the CKD-EPI equation; global GFR was determined by using the DTPA-Tc99m method (A); plasma levels of sodium (Na) and potassium (K) from 2006 to 2021 (B). Regular ICU admissions are noted during the clinical follow-up ()
Fig. 2
Fig. 2
First kidney biopsy showing non caseating granuloma (HE staining, magnification, × 100) (A) epitheloid granuloma (Masson’s trichrome staining, magnification, × 100) (B) and mononuclear cell infiltration (HE staining, magnification, × 100) (C). Second kidney biopsy exhibiting extensive tubulo-interstitial nephritis lesions (PAS staining magnification × 12.8) (D). Image (A,B and C) (scale bar 20 µm), image (D) (scale bar 200 µm)

References

    1. Hilderson I, Van Laecke S, Wauters A, Donck J. Treatment of renal sarcoidosis: is there a guideline? Overview of the different treatment options. Nephrol Dial Transplant. 2014;29:1841–1847. doi: 10.1093/ndt/gft442. - DOI - PubMed
    1. Stehléa T, Boffab J-J, Langa P, Desvauxc D, Sahalia D, Audarda V (2012) Atteintes rénales de la sarcoïdose. Rev Med Interne; pii: S0248–8663(12)00722-9 - PubMed
    1. Bergner R, Löffler C. Renal sarcoidosis: approach to diagnosis and management. Curr Opin Pulm Med. 2018;24:513–520. doi: 10.1097/MCP.0000000000000504. - DOI - PubMed
    1. Correia FASC, Marchini GS, Torricelli FC, Danilovic A, Vicentini FC, Srougi M, Nahas WC, Mazzucchi E. Renal manifestations of sarcoidosis: from accurate diagnosis to specific treatment. Int Braz J Urol. 2020;46:15–25. doi: 10.1590/s1677-5538.ibju.2019.0042. - DOI - PMC - PubMed
    1. Bartter FC, Pronove P, Gill JR, MacCardle RC. Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. A new syndrome. Am J Med. 1962;33(6):811–828. doi: 10.1016/0002-9343(62)90214-0. - DOI - PubMed

Substances