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. 2023 Mar:173:198-203.
doi: 10.1016/j.urology.2022.12.034. Epub 2023 Jan 14.

Phallus Preservation for Locally Advanced Proximal Primary Urethral Carcinoma: Technique and Outcomes

Affiliations

Phallus Preservation for Locally Advanced Proximal Primary Urethral Carcinoma: Technique and Outcomes

Brayden March et al. Urology. 2023 Mar.

Abstract

Introduction: To describe a novel method of penile sparing perineal urethrectomy for locally advanced proximal primary urethral cancers (PUC).

Technical considerations: In mid-2021, 2 cases underwent pelvic exenterative surgery for pT3 and pT4 PUC. The procedure comprised of a complete urethrectomy, proximal penectomy, en bloc pubectomy and excision of pelvic diaphragm in both cases. One case included a wide excision of scrotum, whilst the other required a prostatectomy and abdominoperineal resection of the rectum to achieve complete tumor resection. A complete R0 resection was achieved in both cases. At 6 months follow up, there is no evidence of ischemic necrosis of the penis and cosmesis is satisfactory to both patients. We provide a comprehensive operative description of both cases, together with illustrations, and discuss the underlying principles of penile preservation in the surgical treatment of locally advanced proximal PUC.

Conclusion: Complete perineal urethrectomy with phallic preservation is feasible in men with locally advanced proximal bulbar urethral cancer in the absence of tumor invasion of the penile shaft. The remnant penis survives off arterial supply from the superficial penile arteries arising from the external pudendal arteries. Phallic preservation may benefit patient's psychological quality of life post-procedure.

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