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Review
. 2023 Mar 1;141(3):473-482.
doi: 10.1097/AOG.0000000000005100. Epub 2023 Jan 16.

Coronavirus Disease 2019 (COVID-19) Vaccination in Pregnancy

Malavika Prabhu  1 , Laura E Riley
Affiliations
Review

Coronavirus Disease 2019 (COVID-19) Vaccination in Pregnancy

Malavika Prabhu et al. Obstet Gynecol. .

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy is associated with significant maternal morbidity and mortality, and its risks can be mitigated with coronavirus disease 2019 (COVID-19) vaccination. Vaccination against COVID-19 in pregnancy results in protection against both maternal and neonatal SARS-CoV-2 infection, as well as maternal critical illness. Vaccination during pregnancy is safe, with no documented risks of pregnancy loss, preterm delivery, congenital anomalies, or other adverse perinatal outcomes. For these reasons, COVID-19 vaccination is recommended in pregnancy by the Centers for Disease Control and Prevention, the American College of Obstetricians and Gynecologists, and the Society for Maternal-Fetal Medicine, as well as other national and international professional organizations. In this review, we will summarize the published literature demonstrating the benefit and safety of these vaccines.

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References

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