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Review
. 2023 Apr;20(4):241-258.
doi: 10.1038/s41585-022-00684-0. Epub 2023 Jan 18.

Landmarks in the evolution of prostate biopsy

Martin J Connor #  1   2 , Michael A Gorin #  3 , David Eldred-Evans  4   5 , Edward J Bass  4   5 , Ankit Desai  4 , Tim Dudderidge  6 , Mathias Winkler  4   5 , Hashim U Ahmed  4   5
Affiliations
Review

Landmarks in the evolution of prostate biopsy

Martin J Connor et al. Nat Rev Urol. 2023 Apr.

Abstract

Approaches and techniques used for diagnostic prostate biopsy have undergone considerable evolution over the past few decades: from the original finger-guided techniques to the latest MRI-directed strategies, from aspiration cytology to tissue core sampling, and from transrectal to transperineal approaches. In particular, increased adoption of transperineal biopsy approaches have led to reduced infectious complications and improved antibiotic stewardship. Furthermore, as image fusion has become integral, these novel techniques could be incorporated into prostate biopsy methods in the future, enabling 3D-ultrasonography fusion reconstruction, molecular targeting based on PET imaging and autonomous robotic-assisted biopsy.

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