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. 2023 Mar;46(3):360-368.
doi: 10.1007/s00270-023-03358-5. Epub 2023 Jan 19.

Safety of High-Frequency Jet Ventilation During Image-Guided Thermal Ablation Procedures

Théophane Trochu  1 , Nathalie Desfriches-Doria  2 , Nicolas Grillot  2 , Fanny Feuillet  3 , David Lair  4 , Renan Liberge  5 , Frédéric Douane  5 , Romain Dumont  2 , Arthur David  5
Affiliations

Safety of High-Frequency Jet Ventilation During Image-Guided Thermal Ablation Procedures

Théophane Trochu et al. Cardiovasc Intervent Radiol. 2023 Mar.

Abstract

Rationale and objective: Percutaneous thermal ablative technique is a common radiological procedure for malignant lesions treatment. Controlled assisted ventilation during general anesthesia is the usual mode of ventilation, but high-frequency jet ventilation (HFJV) can be a helpful alternative for the operator. The objective was to evaluate the safety of HFJV during thermal ablation procedures.

Materials and methods: This monocentric prospective analysis included adult patients undergoing percutaneous thermal ablation procedures for abdominal tumor performed under HFJV. Procedures with a transpulmonary path were excluded. The primary outcome was the incidence of respiratory complications. Secondary outcomes included gas exchange modifications (hypercapnia, hypoxemia, pulmonary atelectasis) and the incidence of barotrauma.

Results: Sixty patients were included during the study period. The mean duration time was 88 min. All procedures went according to the protocol and there was no respiratory complication. There was no barotrauma event. Three patients had an exhaled capnia above 45 mmHg at the end of the procedure which normalized within 10 min of conventional ventilation.

Conclusion: HFJV during thermal ablation procedures is safe regarding gas exchange and barotrauma. This technique could be an interesting alternative to conventional ventilation during image-guided thermal ablation procedures. Clinical Trials database This study was registered in Clinical Trials database (NCT04209608).

Keywords: Gas exchange; High-frequency jet ventilation; Percutaneous thermal ablative techniques; Safety.

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