Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jan 19;24(1):17.
doi: 10.1186/s12882-023-03056-x.

Prevalence and incidence of chronic kidney disease stage 3-5 - results from KidDiCo

Jan Dominik Kampmann  1   2 , James Goya Heaf  3 , Christian Backer Mogensen  4   5 , Hans Mickley  6 , Donna Lykke Wolff  7   4 , Frans Brandt  7   4
Affiliations

Prevalence and incidence of chronic kidney disease stage 3-5 - results from KidDiCo

Jan Dominik Kampmann et al. BMC Nephrol. .

Abstract

Background: Chronic kidney disease (CKD) is a global challenge. CKD prevalence estimation is central to management strategies and prevention. It is necessary to predict end stage kidney disease (ESKD) and, subsequently, the burden for healthcare systems. In this study we characterize CKD stage 3-5 prevalence and incidence in a cohort covering the majority of the Region of Southern Denmark and investigate individuals' demographic, socioeconomic, and comorbidity status.

Methods: We used data from the Kidney Disease Cohort (KidDiCo) combining laboratory data from Southern Denmark with Danish national databases. Chronic kidney disease was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines.

Results: The prevalence varied between 4.83 and 4.98% and incidence rate of CKD was 0.49%/year. The median age was 76.4 years. The proportion of individuals with CKD stage 3-5 in the entire population increased consistently with age. The percentage of women in the CKD 3-5 group was higher than in the background population. Diabetes mellitus, hypertension and cardiovascular disease were more prominent in patients with CKD. CKD stage 5 and ESKD were more frequent as incident CKD stages in the 18-49 year olds when compared to older individuals. CKD patients tended to have a lower socioeconomic status.

Conclusion: Chronic kidney disease stage 3-5 is common, especially in the elderly. Patients with CKD stage 3-5 are predominantly female. The KidDiCo data suggests an association between lower socioeconomic status and prevalence of CKD.

Keywords: Chronic kidney Disease; Epidemiology; Prevalence; Socioeconomics.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Age group stratification of incident CKD stage 3–5 patients and the Background population
See this image and copyright information in PMC

References

    1. Bello AK, Levin A, Tonelli M, Okpechi IG, Feehally J, Harris D, et al. Assessment of global kidney health care status. JAMA. 2017;317(18):1864–1881. doi: 10.1001/jama.2017.4046. - DOI - PMC - PubMed
    1. Stack AG, Casserly LF, Cronin CJ, Chernenko T, Cullen W, Hannigan A, et al. Prevalence and variation of chronic kidney Disease in the Irish health system: initial findings from the National Kidney Disease Surveillance Programme. BMC Nephrol. 2014;15:185. doi: 10.1186/1471-2369-15-185. - DOI - PMC - PubMed
    1. Vassalotti JA, Li S, McCullough PA, Bakris GL. Kidney early evaluation program: a community-based screening approach to address disparities in chronic kidney disease. Semin Nephrol. 2010;30(1):66–73. doi: 10.1016/j.semnephrol.2009.10.004. - DOI - PubMed
    1. Matsushita K, Sang Y, Ballew SH, Astor BC, Hoogeveen RC, Solomon SD, et al. Cardiac and kidney markers for cardiovascular prediction in individuals with chronic kidney disease: the atherosclerosis risk in communities study. Arterioscler Thromb Vasc Biol. 2014;34(8):1770–1777. doi: 10.1161/ATVBAHA.114.303465. - DOI - PMC - PubMed
    1. Collins AJ, Foley RN, Herzog C, Chavers B, Gilbertson D, Ishani A, et al. United States renal data system 2008 annual data report. Am J Kidney Dis. 2009;53(1 Suppl):S1–374. - PubMed

Publication types