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. 2023 Jan 19;24(1):46.
doi: 10.1186/s12891-023-06147-w.

Differences in the prevalence and risk factors of osteoporosis in chinese urban and rural regions: a cross-sectional study

Miao Zheng #  1 , Yanan Wan #  2 , Gongwen Liu #  3 , Yan Gao  4 , Xiaoqun Pan  2 , Wanxi You  5 , Donglan Yuan  6 , Jianxin Shen  7 , Junhua Lu  8 , Xia Wang  9 , Gangfeng Zheng  10 , Zhiqiang Han  11 , Xinlin Li  12 , Kai Chen  13 , Xiaoxi Xing  14 , Dong Zhang  1 , Chengwei Weng  1 , Qi Wei  15 , Yongqing Zhang  16 , Hua Lin  17
Affiliations

Differences in the prevalence and risk factors of osteoporosis in chinese urban and rural regions: a cross-sectional study

Miao Zheng et al. BMC Musculoskelet Disord. .

Abstract

Background: Bone mineral density (BMD) and prevalence of osteoporosis may differ between urban and rural populations. This study aimed to investigate the differences in BMD characteristics between urban and rural populations in Jiangsu, China.

Methods: A total of 2,711 participants aged 20 years and older were included in the cross-sectional study. Multistage and stratified cluster random sampling was used as the sampling strategy. BMD was measured by the method of dual-energy x-ray absorptiometry (DXA). Data were collected through questionnaires/interview. BMD values at the lumbar spine (L1-L4), femoral neck, total hip, and greater trochanter were collected. Descriptive statistics were used to demonstrate the characteristics of urban and rural participants. Multivariate logistic regression analysis was utilized to analyze the factors that may be associated with osteoporosis in urban and rural populations.

Results: Of these participants, 1,540 (50.49%) were females and 1,363 (42.14%) were from urban. The prevalence of osteoporosis in urban and rural populations was 5.52% and 10.33%, respectively. In terms of gender, the prevalence of osteoporosis was 2.68% in males and 13.82% in females. For menopausal status, the prevalence of osteoporosis was 30.34% in postmenopausal females and 4.78% in premenopausal females. In urban populations, older age [adjusted odds ratio (AOR) = 2.36, 95%CI, 2.35-2.36), hypertension (AOR = 1.37, 95%CI, 1.36-1.37), unmarried (AOR = 4.04, 95%CI, 3.99-4.09), smoking everyday (AOR = 2.26, 95%CI, 2.23-2.28), family history of osteoporosis (AOR = 1.66, 95%CI, 1.65-1.67), dyslipidemia (AOR = 1.05, 95%CI, 1.04-1.05), and higher β-crosslaps (β-CTX) level (AOR = 1.02, 95%CI, 1.02-1.02) were associated with an increased risk of osteoporosis, while males (AOR = 0.04, 95%CI, 0.04-0.04), higher education level (AOR = 0.95, 95%CI, 0.95-0.95), and aquatic product intake (AOR = 0.99, 95%CI, 0.99-0.99) were related to decreased risk of osteoporosis. Similar results were also observed in rural populations, and (all P < 0.05).

Conclusion: The prevalence of osteoporosis in rural populations was higher than that in urban populations, and the factors associated with the risk of osteoporosis were similar in urban and rural populations.

Keywords: Influencing factor; Osteoporosis; Prevalence; Urban and rural.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
The prevalence of osteoporosis in different populations
Fig. 2
Fig. 2
Curves of bone mineral density (BMD) with age at the greater trochanter and total hip in men, premenopausal women and postmenopausal women. A BMD of greater trochanter; B BMD of total hip
See this image and copyright information in PMC

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