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Review
. 2023 Jan 20.
doi: 10.1111/prd.12473. Online ahead of print.

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Georgios N Belibasakis  1 , Daniel Belstrøm  2 , Sigrun Eick  3 , Ulvi K Gursoy  4 , Anders Johansson  5 , Eija Könönen  4
Affiliations
Free article
Review

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Georgios N Belibasakis et al. Periodontol 2000. .
Free article

Abstract

This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis-centered interpretation. Reference is made to anerobic microbiology and to the discovery of select periodontal pathogens and their virulence factors, as well as to biofilms. The evolution of contemporary molecular methods and high-throughput platforms is highlighted in appreciating the breadth and depth of the periodontal microbiome. Finally clinical microbiology is brought into perspective with the contribution of different microbial species in periodontal diagnosis, the combination of microbial and host biomarkers for this purpose, and the use of antimicrobials in the treatment of the disease.

Keywords: European; anaerobic; antibiotics; antimicrobial; biofilms; clinical microbial diagnostics; etiology; host biomarkers; pathogens; periodontal microbiology.

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References

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