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Comment
. 2023 May;201(4):599-601.
doi: 10.1111/bjh.18651. Epub 2023 Jan 20.

A 'needle in a haystack': Drug-induced thrombotic thrombocytopenic purpura-Association or causality?

Marie Scully  1
Affiliations
Comment

A 'needle in a haystack': Drug-induced thrombotic thrombocytopenic purpura-Association or causality?

Marie Scully. Br J Haematol. 2023 May.

Abstract

The risk of a drug associated with thrombotic thrombocytopenic purpura (TTP) demonstrating causality is rare, but it is important to keep an open mind of possible associations. Use of criteria to ascertain causality of drugs that may be related to thrombotic microangiopathies and exclude TTP, may be a useful resource. Commentary on: Schofield et al. Drug-induced thrombotic thrombocytopenic purpura: A systematic review and review of European and North American pharmacovigilance data. Br J Haematol 2023;200:766-773.

Keywords: causality; drugs; thrombotic microangiopathy (TMA); thrombotic thrombocytopenic purpura (TTP).

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  • Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.
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References

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