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Review
. 2022 Dec 27;10(1):62.
doi: 10.3390/children10010062.

Advances in the Treatment of Pediatric Brain Tumors

Edwin S Kulubya  1 , Matthew J Kercher  1 , H Westley Phillips  2 , Reuben Antony  3 , Michael S B Edwards  1
Affiliations
Review

Advances in the Treatment of Pediatric Brain Tumors

Edwin S Kulubya et al. Children (Basel). .

Abstract

Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy.

Keywords: brain tumors; ependymoma; glioma; immunotherapy; laser interstitial therapy; medulloblastoma; pediatrics; targeted therapy.

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Conflict of interest statement

The authors declare no conflict of interest.

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