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Review
. 2022 Dec 23;11(1):33.
doi: 10.3390/biomedicines11010033.

The Role of Sympathetic Nerves in Osteoporosis: A Narrative Review

Weifei Zhang  1 , Yuheng Liu  1 , Jixuan Xu  2 , Chen Fan  2 , Bin Zhang  3 , Pin Feng  3 , Yu Wang  1 , Qingquan Kong  1   3
Affiliations
Review

The Role of Sympathetic Nerves in Osteoporosis: A Narrative Review

Weifei Zhang et al. Biomedicines. .

Abstract

Osteoporosis, a systemic bone disease, is characterized by decreased bone density due to various reasons, destructed bone microstructure, and increased bone fragility. The incidence of osteoporosis is very high among the elderly, and patients with osteoporosis are prone to suffer from spine fractures and hip fractures, which cause great harm to patients. Meanwhile, osteoporosis is mainly treated with anti-osteoporosis drugs that have side effects. Therefore, the development of new treatment modalities has a significant clinical impact. Sympathetic nerves play an important role in various physiological activities and the regulation of osteoporosis as well. Therefore, the role of sympathetic nerves in osteoporosis was reviewed, aiming to provide information for future targeting of sympathetic nerves in osteoporosis.

Keywords: osteoporosis; sympathetic nerves.

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Conflict of interest statement

The authors declare no competing interest.

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