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. 2022 Dec 23;13(1):26.
doi: 10.3390/jpm13010026.

Responses at Individual Gamma Frequencies Are Related to the Processing Speed but Not the Inhibitory Control

Inga Griškova-Bulanova  1 , Marko Živanović  2 , Aleksandras Voicikas  1 , Evaldas Pipinis  1 , Vytautas Jurkuvėnas  3 , Jovana Bjekić  4
Affiliations

Responses at Individual Gamma Frequencies Are Related to the Processing Speed but Not the Inhibitory Control

Inga Griškova-Bulanova et al. J Pers Med. .

Abstract

The link between the state of networks underlying the generation of periodic responses at gamma ranges and cognitive outcomes is still poorly understood. In this study, we tested the idea that the individual differences in the ability to generate responses to auditory stimulation at gamma frequencies may underlie the individual differences in the inhibitory control. We focused on the processing speed and accuracy in the Bivalent Shape Task (a cognitive inhibition task assessing attentional interference) and explored the relationship with responses at 40 Hz and at individual gamma frequencies (IGFs, assessed utilizing auditory envelope-following responses in 30-60 Hz range). In a sample of 70 subjects, we show that individual measures (phase-locking index and event-related spectral perturbation) of the ability to generate gamma-range activity are not related to the individual differences in inhibitory control but rather reflect basic information processing speed in healthy young subjects. With the individualized approach (at IGFs), the observed associations were found to be somewhat stronger. These findings have important implications for the interpretation of gamma activity in neuropsychiatric disorders.

Keywords: auditory steady-state response (ASSR); cognitive performance; envelope-following response (EFR); gamma; individual resonant frequency; inhibition.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

Figures

Figure 1
Figure 1
Bivalent Shape Task. Six stimuli were used in the task: the circle in blue color (congruent condition; correct response: left), red (incongruent condition, correct response: left), and no color (neutral condition; correct response: left), and the square in red color (congruent; correct response: right), blue (incongruent; correct response: right), and no color (neutral correct response: right).
Figure 2
Figure 2
(A) The grand averaged time–frequency plot of the phase-locking index alongside the topographic activation plots at selected frequencies. (B) The individual phase-locking index curves and distribution of IGF. (C) Scatterplots of PLI values obtained at IGFs against reaction times in congruent, neutral, and incongruent conditions of the Bivalent Shape Task. a.u.—arbitrary units.
See this image and copyright information in PMC

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