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Review
. 2023 Jan 8;13(1):178.
doi: 10.3390/life13010178.

Evaluation of the Phytochemistry-Therapeutic Activity Relationship for Grape Seeds Oil

Manuel Alexandru Gitea  1 , Simona Gabriela Bungau  2   3 , Daniela Gitea  2 , Bianca Manuela Pasca  2 , Anamaria Lavinia Purza  2 , Andrei-Flavius Radu  3
Affiliations
Review

Evaluation of the Phytochemistry-Therapeutic Activity Relationship for Grape Seeds Oil

Manuel Alexandru Gitea et al. Life (Basel). .

Abstract

Seeds' abundant biologically active compounds make them a suitable primary platform for the production of natural extracts, innovative foods, medicines, and cosmetics. High levels of industrial and agricultural residues and byproducts are generated during the processing of grapes, although some parts can also be repurposed. This paper examines the phytochemical composition, manufacturing processes, and health-improving attributes of many varieties of grape oil derived using various extraction methods. Since the results are influenced by a range of factors, they are expressed differently among studies, and the researchers employ a variety of measuring units, making it difficult to convey the results. The primary topics covered in most papers are grape seed oil's lipophilic fatty acids, tocopherols, and phytosterols. In addition, new methods for extracting grape seed oil should therefore be designed; these methods must be affordable, energy-efficient, and environmentally friendly in order to increase the oil's quality by extracting bioactive components and thereby increasing its biological activity in order to become part of the overall management of multiple diseases.

Keywords: Vitis vinifera L.; bioactive compounds; biologic activity; extraction techniques; grape seeds oil; phytochemistry; therapeutic activity.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
General classification of predominant fatty acids detected in GSO.
Figure 2
Figure 2
Literature selection depicted in a PRISMA 2020 flow diagram.
Figure 3
Figure 3
Taxonomical classification of Vitis vinifera L.
Figure 4
Figure 4
Methods of obtaining grape seed oil.
Figure 5
Figure 5
The chemical structure of several tocopherol and tocotrienol types.
Figure 6
Figure 6
Concentration of tocopherols and tocotrienols in GSO.
Figure 7
Figure 7
Chemical structure of the most common phytosterols identified GSO.
Figure 8
Figure 8
Classification of common polyphenols identified in GSO.
Figure 9
Figure 9
Correlation between several plant parts and their therapeutic actions.
Figure 10
Figure 10
Registered patents with GSO.
See this image and copyright information in PMC

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