Advancing Immunization Coverage and Equity: A Structured Synthesis of Pro-Equity Strategies in 61 Gavi-Supported Countries
- PMID: 36680034
- PMCID: PMC9865353
- DOI: 10.3390/vaccines11010191
Advancing Immunization Coverage and Equity: A Structured Synthesis of Pro-Equity Strategies in 61 Gavi-Supported Countries
Abstract
Background: Global immunization inequities persist, reflected in the 25 million underimmunized and 18 million zero-dose children in 2021. To identify country approaches to reach underimmunized and zero-dose children, we undertook a structured synthesis of pro-equity strategies across 61 countries receiving programmatic support from Gavi, the Vaccine Alliance.
Methods: We extracted data from 174 Country Joint Appraisals and Multi-Stakeholder Dialogue reports (2016-2020). We identified strategies via a targeted keyword search, informed by a determinants of immunization coverage framework. Strategies were synthesized into themes consolidated from UNICEF's Journey to Health and Immunization (JTHI) and the Global Routine Immunization Strategies and Practices (GRISP) frameworks.
Results: We found 607 unique strategies across 61 countries and 24 themes. Strategies to improve care at the point of service (44%); to improve knowledge, awareness and beliefs (25%); and to address preparation, cost and effort barriers (13%) were common. Fewer strategies targeted experience of care (8%), intent, (7%) and after-service (3%). We also identified strategies addressing gender-related barriers to immunization and targeting specific types of communities.
Conclusions: We summarize the range of pro-equity immunization strategies employed in Gavi-supported countries and interpret them thematically. Findings are incorporated into a searchable database which can be used to inform equity-driven immunization programs, policies and decision-making which target underimmunized and zero-dose communities.
Keywords: children; conflict; equity; gender; immunization; poor; remote; rural; urban.
Conflict of interest statement
The authors declare no conflict of interest.
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References
-
- UNICEF Vaccination and Immunization Statistics: UNICEF Data 2022. [(accessed on 18 December 2022)]. Available online: https://data.unicef.org/topic/child-health/immunization/
-
- WHO Immunization Agenda 2030: Framework for Action—Annex 1. 2020. [(accessed on 18 December 2022)]. Available online: https://www.immunizationagenda2030.org/framework-for-action.
-
- Ali H.A., Hartner A.M., Echeverria-Londono S., Roth J., Li X., Abbas K., Portnoy A., Vynnycky E., Woodruff K., Ferguson N.M., et al. Vaccine equity in low and middle income countries: A systematic review and meta-analysis. Int. J. Equity Health. 2022;21:82. doi: 10.1186/s12939-022-01678-5. - DOI - PMC - PubMed
-
- Gavi, the Vaccine Alliance The Zero-Dose Child: Explained. 2021. [(accessed on 18 December 2022)]. Available online: https://www.gavi.org/vaccineswork/zero-dose-child-explained.
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