FAP: Not Just a Biomarker but Druggable Target in Liver Fibrosis
- PMID: 36681094
- PMCID: PMC10040959
- DOI: 10.1016/j.jcmgh.2022.12.018
FAP: Not Just a Biomarker but Druggable Target in Liver Fibrosis
Comment on
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Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis.Cell Mol Gastroenterol Hepatol. 2023;15(4):841-867. doi: 10.1016/j.jcmgh.2022.12.005. Epub 2022 Dec 13. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36521660 Free PMC article.
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- Levy M.T., McCaughan G.W., Marinos G., et al. Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection. Liver. 2002;22:93–101. - PubMed
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- Levy M.T., McCaughan G.W., Abbott C.A., et al. Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis. Hepatology. 1999;29:1768–1778. - PubMed
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- Wang X.M., Yu D.M., McCaughan G.W., et al. Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line. Hepatology. 2005;42:935–945. - PubMed
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