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Review
. 2023 Jan 4:10:1092809.
doi: 10.3389/fped.2022.1092809. eCollection 2022.

Dental caries and periodontitis risk factors in cleft lip and palate patients

Qinrui Wu  1   2 , Zhengyi Li  1 , Yixin Zhang  1   2 , Xian Peng  1 , Xuedong Zhou  1   2
Affiliations
Review

Dental caries and periodontitis risk factors in cleft lip and palate patients

Qinrui Wu et al. Front Pediatr. .

Abstract

Cleft lip and palate (CLP) is the most common congenital facial malformation and has a significant developmental, physical, and psychological impact on those with the deformity and their families. Risk factors contributing to CLP may conclude as genetic factors and environmental factors. The anatomical and morphological abnormalities related to CLP are favorable for dental plaque accumulation on the tooth surface. Therefore, patients with CLP undergo poorer oral hygiene and higher susceptibility to dental caries and periodontitis. In this review, we aim to conclude and update probable causes underlying the association between CLP and poor oral health and provide novel ideas of targeted early prevention for such oral diseases.

Keywords: alveolar bone deformity; cleft lip and palate; dental caries; microbial dysbiosis; oral hygiene; periodontitis; tooth deformity.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Embryonic development in oral and maxillofacial region. (A) embryonic week 4. (B) embryonic week 6. (C) developed lip and palate. Cleft phenotypes (D) Normal cleft lip. (E) unilateral cleft lip and palate (UCLP) and (F) bilateral cleft lip and palate (BCLP).
Figure 2
Figure 2
Patients with cleft lip and palate undergo poorer oral hygiene as a result of alveolar deformity, tooth deformity, microbial dysbiosis, surgical repair, orthodontic treatment and appliance wear.
See this image and copyright information in PMC

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