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. 2023 Jan 6:9:1003854.
doi: 10.3389/fsurg.2022.1003854. eCollection 2022.

Double-stapled anastomosis without "dog-ears" reduces the anastomotic leakage in laparoscopic anterior resection of rectal cancer: A prospective, randomized, controlled study

Yuanfeng Yang  1 , Feng Ding  1 , Tianbao Xu  1 , Zhen Pan  1 , Jinfu Zhuang  1 , Xing Liu  1 , Guoxian Guan  1   2
Affiliations

Double-stapled anastomosis without "dog-ears" reduces the anastomotic leakage in laparoscopic anterior resection of rectal cancer: A prospective, randomized, controlled study

Yuanfeng Yang et al. Front Surg. .

Abstract

Background: Anastomotic leakage (AL) is a major cause of postoperative morbidity and mortality in the treatment of colorectal cancer. The aim of this study was to investigate whether the resection of "dog-ears" in laparoscopic anterior resection of rectal cancer (called modified double-stapling technique, MDST) could reduce the rate of AL in patients with middle and high rectal cancer, as compared with the conventional double-stapling technique (DST).

Methods: The clinical data of 232 patients with middle and high rectal cancer were prospectively collected from September 2015 to October 2018. They were randomly divided into the MDST group (n = 116) and the DST group (n = 116) and the data were prospectively analyzed. Morbidity and AL rate were compared between the two groups.

Results: Patient demographics, tumor size, and time of first flatus were similar between the two groups. No difference was observed in the operation time between the two groups. The AL rate was significantly lower in the MDST group than in the DST group (3.4 vs. 11.2%, p = 0.032). The age and anastomotic technique were the factors associated with AL according to the multivariate analysis. The location of the AL in the DST group was further investigated, revealing that AL was in the same place as the "dog-ears" (11/13, 84.6%).

Conclusions: Our prospective comparative study demonstrated that MDST have a better short-term outcome in reducing AL compared with DST. Therefore, this technique could be an alternative approach to maximize the benefit of laparoscopic anterior resection on patients with middle and high rectal cancer. The "dog-ears" create stapled corners potentially ischemic, since they represent the area with high incidence of AL.(NCT:02770911).

Keywords: anastomotic leakage; anterior resection; laparoscopic; middle and high rectal cancer; modified double-stapling technique.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The patients flow chart.
Figure 2
Figure 2
End-to-end anastomosis by DST and MDST. (A) Suturing two corners of the staple line around the trocar; (B) Without “dog ears” after anastomosis; (C) Distal rectum with “dog ears”; (D) With “dog ears” after anastomosis.
Figure 3
Figure 3
Diagram of AL. (A) The colonoscopy of the AL patinets. (B) and (C) The x-ray of the AL patinets.
See this image and copyright information in PMC

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