Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Jan 15;18(3):1297-1301.
doi: 10.1016/j.radcr.2022.12.070. eCollection 2023 Mar.

Carcinosarcoma of uterus

Ho Xuan Tuan  1 , Nguyen Minh Duc  2   3 , Cao Minh Tri  2 , Huynh-Thi Do Quyen  2 , Pham Xuan Dung  4
Affiliations
Case Reports

Carcinosarcoma of uterus

Ho Xuan Tuan et al. Radiol Case Rep. .

Abstract

Uterine carcinosarcoma, which is categorized as high-grade endometrial cancer, is an uncommon kind of malignant gynecological neoplasms. Clinically, this tumor frequently affects menopausal women and the main symptom is abnormally postmenopausal vaginal bleeding. Surgery continues to be the main treatment for carcinosarcoma. In this study, we wanted to discuss 2 cases of uterine carcinosarcoma in 2 women who were in menopause and who had been evaluated by ultrasound and magnetic resonance imaging.

Keywords: Carcinosarcoma; Magnetic resonance imaging; Ultrasound; Uterus.

PubMed Disclaimer

Figures

Fig 1
Fig. 1
A heterogeneous mass (arrows) can be seen inside the uterus on the sagittal T2W (A). On T1W with contrast agent, the lesion showed weak enhancement (B). Within the mass, there are several regions with limited diffusion (arrow) on DWI (C) and matching low signal on the ADC map (D).
Fig 2
Fig. 2
Pelvic ultrasonography shows ill-defined border tumor inside the uterus with a heterogeneous echotexture (arrow).
Fig 3
Fig. 3
The axial precontrast T1-weighted (A) and T2-weighted (B) MRI images demonstrate a heterogeneous mass (arrows) centered within the uterus. Within the mass, there are several regions with limited diffusion (arrows, (C, D) showing strong signal on DWI (C) and matching low signal on the ADC map (D). On postcontrast axial (E) and sagittal (F) T1-weighted fat-saturated images, the lesion shows heterogeneously enhanced (arrow).
See this image and copyright information in PMC

References

    1. Kurnit KC, Previs RA, Soliman PT, Westin SN, Klopp AH, Fellman BM, et al. Prognostic factors impacting survival in early stage uterine carcinosarcoma. Gynecol Oncol. 2019;152(1):31–37. doi: 10.1016/j.ygyno.2018.10.034. - DOI - PMC - PubMed
    1. Cantrell LA, Blank SV, Duska LR. Uterine carcinosarcoma: a review of the literature. Gynecol Oncol. 2015;137(3):581–588. doi: 10.1016/j.ygyno.2015.03.041. - DOI - PubMed
    1. Matsuo K, Ross MS, Machida H, Blake EA, Roman LD. Trends of uterine carcinosarcoma in the United States. J Gynecol Oncol. 2018;29(2):e22. doi: 10.3802/jgo.2018.29.e22. - DOI - PMC - PubMed
    1. Fader AN, Java J, Tenney M, Ricci S, Gunderson CC, Temkin SM, et al. Impact of histology and surgical approach on survival among women with early-stage, high-grade uterine cancer: an NRG Oncology/Gynecologic Oncology Group ancillary analysis. Gynecol Oncol. 2016;143(3):460–465. doi: 10.1016/j.ygyno.2016.10.016. - DOI - PMC - PubMed
    1. Desai NB, Kollmeier MA, Makker V, Levine DA, Abu-Rustum NR, Alektiar KM. Comparison of outcomes in early stage uterine carcinosarcoma and uterine serous carcinoma. Gynecol Oncol. 2014;135(1):49–53. doi: 10.1016/j.ygyno.2014.07.097. - DOI - PubMed

Publication types

LinkOut - more resources