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Case Reports
. 2023 Jan 11:2023:8864790.
doi: 10.1155/2023/8864790. eCollection 2023.

A Case of Feline Leishmaniosis with Panniculitis

Dimitrios Matralis  1 , Ioanna Papadogiannaki  1 , Evi Gkerdidani  1 , Eleni Patsoula  2 , Nikolaos Tegos  2 , Emmanouil Papadogiannakis  2
Affiliations
Case Reports

A Case of Feline Leishmaniosis with Panniculitis

Dimitrios Matralis et al. Case Rep Vet Med. .

Abstract

Leishmaniases are a group of diseases caused by protozoa of the genus Leishmania and transmitted mainly by the bite of sand fly vectors. Cats are infected with at least 6 species of Leishmania. Significant associations have been found between feline leishmaniosis and coinfections mainly with FIV and/or FeLV. A 7-year-old castrated male, domestic short-haired cat was presented with unknown history and cutaneous and ocular lesions. A raised, semifirm swelling on the forehead was observed along with periocular hypotrichosis and conjunctival and third eyelid edema. The indications for pursuing a diagnosis of leishmaniosis are variable, and differing presentations may require the use of different tests. Diagnosis of feline leishmaniosis with panniculitis caused by Leishmania infantum was made by cytology, histopathology, and PCR and Leishmania antibodies (IFA). The cat responded to therapy with meglumine antimoniate and allopurinol.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Swelling on the forehead is obvious along with periocular hypotrichosis.
Figure 2
Figure 2
Edema of the conjunctiva and third eyelid of the right eye.
Figure 3
Figure 3
Photomicrography of the swelling of the forehead of the cat with leishmaniosis showing granulomatous inflammation with high number of Leishmania amastigotes, both intracellularly (arrowhead) and extracellularly (arrow). In some amastigotes, the basophilic rod-shaped kinetoplast is clearly visible (asterisk) (Diff-Quick stain, x400).
Figure 4
Figure 4
Photomicrography showing granulomatous panniculitis with high number of Leishmania amastigotes (Hematoxylin and Eosin stain, x400).
Figure 5
Figure 5
PCR amplified products (lanes 1 and 6: 100 bp DNA ladder; lane 2: FNAB sample; lane 3: positive control for L. infantum; lane 4: ATCC NR-50127 positive control for L. tropica; lane 5: negative control).
Figure 6
Figure 6
Four months after the start of therapy, the cat looks normal.
See this image and copyright information in PMC

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