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. 2023 Jan 5:13:1036122.
doi: 10.3389/fphys.2022.1036122. eCollection 2022.

The effect of loss of foot sole sensitivity on H-reflex of triceps surae muscles and functional gait

Fangtong Zhang  1 , Mengzi Sun  2   3 , Feng Qu  1 , Kelsey Lewis  2 , Jung Hun Choi  4 , Qipeng Song  5 , Li Li  2
Affiliations

The effect of loss of foot sole sensitivity on H-reflex of triceps surae muscles and functional gait

Fangtong Zhang et al. Front Physiol. .

Abstract

Objective: To investigate the effects of foot sole insensitivity on the outcomes of the triceps surae muscle H-reflex and functional gait. Material and Methods: People with peripheral neuropathy were recruited and divided into two groups: people with more (n = 13, 73.3 ± 4.3 years old) or less (n = 10, 73.5 ± 5.3) sensitive tactile sensation. Their monofilament testing scores were 9.0 ± 1.5 (range: 7-10) and 2.3 ± 2.4 (range: 0-6) out of 10, respectively. H-reflex of the triceps surae muscles during quiet standing and their relationship with functional gait, 6 min walking distance (6MWD), and timed-up-and-go duration (TUG), were compared between groups. Results: No significant difference was detected for H-reflex parameters between the groups. The less sensitive group showed reduced (p < .05) functional gait capacity compared to the other group, 38.4 ± 52.7 vs. 463.5 ± 47.6 m for 6MWD, and 9.0 ± 1.5 vs. 7.2 ± 1.1s for TUG, respectively. A significant correlation (p < .05), worse functional gait related to greater H/M ratio, was observed in the less sensitive group, not the other group. Conclusion: Although there was no significant H-reflex difference between the groups, more pronounced tactile sensation degeneration affected functional gaits and their relationship with H-reflex.

Keywords: H-reflex; foot sole sensitivity; functional gait; motor control; triceps surae muscles.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Exemplar EMG signal of a stimulus of triceps surae muscles within 50 milliseconds before the start of stimulus and after the end of the H-wave.
FIGURE 2
FIGURE 2
(A) H/M ratio (solid) and H-index (dashed) of the MG, LG, and SO muscles were compared. There were no differences between groups in H/M ratio and H-index (p > .05). H/M ratio of SO was significantly greater than that of both MG (p < .001, d = .232) and LG (p < .001, d = .098). No difference in H-index was detected among different muscles (B) MST and LST groups were compared for both 6MWD (solid, p = .006, partial η2 = .318) and TUG (dash, p = .011, partial η2 = .282). The MST group walked farther (6MWD) and fast (TUG) than the LST group. *Indicates a significant difference between muscles (left) or groups (right).
FIGURE 3
FIGURE 3
A significant linear relationship between the H/M ratio of SO and MG [(A) only in MST group] and the linear relationships between the H/M ratio of SO and LG [(B) among both MST and LST groups] were detected.
FIGURE 4
FIGURE 4
The linear relationship between the H-index of MG and LG with only significant correlation was detected in the MST group.
FIGURE 5
FIGURE 5
Significant linear relationships were only observed in LST between the H/M ratio of LG and 6MWD (A), and TUG (B), and of SO and TUG (C). Note: the range of SO H/M ratio was much greater than that of the LG.
FIGURE 6
FIGURE 6
The significant linear relationship between TUG and the H-index of MG in the MST group.
See this image and copyright information in PMC

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References

    1. Alfuth M., Rosenbaum D. (2012). Effects of changes in plantar sensory feedback on human gait characteristics: A systematic review. Footwear Sci. 4 (1), 1–22. 10.1080/19424280.2011.653990 - DOI
    1. Allen M. D., Major B., Kimpinski K., Doherty T. J., Rice C. L. (2014). Skeletal muscle morphology and contractile function in relation to muscle denervation in diabetic neuropathy. J. Appl. Physiology 116 (5), 545–552. 10.1152/japplphysiol.01139.2013 - DOI - PMC - PubMed
    1. Alrowayeh H. N., Sabbahi M. A., Etnyre B. (2011). Similarities and differences of the soleus and gastrocnemius H-reflexes during varied body postures, foot positions, and muscle function: Multifactor designs for repeated measures. BMC Neurol. 11 (1), 65. 10.1186/1471-2377-11-65 - DOI - PMC - PubMed
    1. Alvarez F. J., Bullinger K. L., Titus H. E., Nardelli P., Cope T. C. (2010). Permanent reorganization of Ia afferent synapses on motoneurons after peripheral nerve injuries. Ann. N. Y. Acad. Sci. 1198, 231–241. 10.1111/j.1749-6632.2010.05459.x - DOI - PMC - PubMed
    1. Awiszus F., Feistner H. (1993). The relationship between estimates of Ia-EPSP amplitude and conduction velocity in human soleus motoneurons. Exp. Brain Res. 95 (2), 365–370. 10.1007/BF00229795 - DOI - PubMed

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