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. 2022 Sep;8(3):226-232.
doi: 10.5114/ceh.2022.119246. Epub 2022 Sep 14.

Outcomes of endoscopic retrograde cholangio-pancreatography in patients with liver transplant

Tsujung Yang  1 , Achint Patel  2 , Rishita Pujari  3 , Vincent P Okine  4 , Lakshmi G Chirumamilla  5 , Geethu Jnaneswaran  6 , Athul Raj  7 , Keji L Kwajok  8 , Ruchir Goswami  9 , Prakashkumar Maiyani  10 , Maheshkumar Desai  11 , Hardikkumar Shah  12 , Matthew Grossman  12
Affiliations

Outcomes of endoscopic retrograde cholangio-pancreatography in patients with liver transplant

Tsujung Yang et al. Clin Exp Hepatol. 2022 Sep.

Abstract

Aim of the study: Biliary complications are the leading causes of morbidity and mortality after liver transplant (LT). However, national data on endoscopic retrograde cholangiopancreatography (ERCP) usage and outcomes in LT patients are lacking. Our study aims to identify the trends, outcomes, and predictors of ERCP and related complications in this patient subgroup.

Material and methods: We derived our study cohort from the Nationwide Inpatient Sample (NIS) of the Healthcare Cost and Utilization Project (HCUP) between 2007 and 2017. LT patients were identified using ICD-9/10CM diagnosis codes and patients who underwent ERCP were identified by ICD-9/10-CM procedure codes. We utilized the Cochrane-Armitage trend test and multivariate logistic regression to analyze temporal trends, outcomes, and predictors.

Results: A total of 372,814 hospitalizations occurred in LT patients between 2007 and 2017. ERCP was performed in 2.05% (n = 7632) of all hospitalizations. There was a rise in ERCP procedures from 1.96% (n = 477) in 2007 to 2.05% (n = 845) in 2017. Among LT patients who underwent ERCP, the in-hospital mortality rate was 1% (n = 73) and 8% (n = 607) were discharged to facilities. Mean length of hospital stay was 7 ±0.3 days. Septicemia was the most common periprocedural complication (18.3%, n = 1399) followed by post-ERCP pancreatitis (8.8%, n = 674).

Conclusions: There has been an increase in ERCP procedures over the past decade among LT patients. Our study highlights the periprocedural complications and outcomes of ERCP in LT patients from a nationally representative dataset.

Keywords: endoscopic retrograde cholangiopancreatography; liver transplant; outcomes; predictors; trends.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Trends of endoscopic retrograde cholangiopancreatography among liver transplant patients
Fig. 2
Fig. 2
Temporal trends of discharge disposition among liver transplant patients undergoing endoscopic retrograde cholangiopancreatography
See this image and copyright information in PMC

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