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. 1987 Nov;49(5):1348-54.
doi: 10.1111/j.1471-4159.1987.tb00998.x.

Primary structure and tissue distribution of guinea pig gastrin-releasing peptide

C Shaw  1 , L Thim, J M Conlon
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Primary structure and tissue distribution of guinea pig gastrin-releasing peptide

C Shaw et al. J Neurochem. 1987 Nov.

Abstract

The primary structure of gastrin-releasing peptide from the guinea pig stomach has been determined by automated Edman degradation and shown to be identical to porcine gastrin-releasing peptide. Extracts of guinea pig brain and small intestine contained both gastrin-releasing peptide and its COOH-terminal decapeptide (neuromedin C) but the stomach extracts contained only gastrin-releasing peptide. Within the small intestine, highest concentrations of gastrin-releasing peptide-like immunoreactivity were found in extracts of the circular and longitudinal smooth muscle layers.

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