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. 2023 Jan 16;12(1):22799036221150062.
doi: 10.1177/22799036221150062. eCollection 2023 Jan.

Sociodemographic and clinical variables as determinants of mortality and survival in patients with acute ST-elevation myocardial infarction in the Eastern Amazon

Tárcio Sadraque Gomes Amoras  1   2 , Thalia Saraiva Mendonça  1 , Giovana Salomão Melo  1 , Kleber Renato Ponzi Pereira  2 , Christielaine Venzel Zaninotto  2 , Sheila Santos de Oliveira  2 , Rosana Moreira da Silva  2 , Fabiana Campos Gomes  3 , João Simão de Melo Neto  1
Affiliations

Sociodemographic and clinical variables as determinants of mortality and survival in patients with acute ST-elevation myocardial infarction in the Eastern Amazon

Tárcio Sadraque Gomes Amoras et al. J Public Health Res. .

Abstract

Background: The aim of this study was to analyze the influence of sociodemographic and clinical variables as determinants of mortality and survival in patients with ST-segment elevation acute myocardial infarction in the Eastern Amazon.

Design and methods: This observational, longitudinal, and retrospective study was conducted at the Gaspar Vianna Clinical Hospital Foundation in patients hospitalized from January 2017 to June 2020. Patients were divided into two groups: those who survived (G1) (n = 646) and those who died (G2) (n = 37). Sociodemographic and clinical variables associated with mortality and survival in these two groups were analyzed.

Results: Patients with STEMI who had the highest risk of death were often the oldest (G1: 61.58 ± 10.74 years; G2: 69.57 ± 9.02 years; t = -4.492; p = 0.001), with Killip III-IV classifications (OR = 0.13; 95% CI = 0.02-0.71; p = 0.03), and with diseases such as heart failure (OR = 0.07; 95% CI = 0.004-1.50; p = 0.168) or renal failure (OR = 0.03; 95% CI = 0.006-0.16; p = 0.0001). In addition, female sex (hazard ratio = 2.073; 95% CI = 1.413-5.170), Killip III-IV classifications (hazard ratio = 4.041; 95% CI = 1.703-18.883) and the presence of heart failure (hazard ratio = 34.102; 95% CI = 4.410-263.684) or renal failure (hazard ratio = 14.278; 95% CI = 3.275-62.248) shortened in-hospital survival.

Conclusions: Specific sociodemographic and clinical aspects influenced mortality and survival in patients with acute ST -elevation myocardial infarction.

Keywords: Myocardial infarction; ST elevation myocardial infarction; mortality; survival analysis.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Kaplan-Meier survival curves of patients hospitalized with ST-segment elevation myocardial infarction, according to sex (a), heart failure (b), chronic kidney disease (c) and Killip classification (d), being performed Cox regression (e).
See this image and copyright information in PMC

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