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Review
. 2023 Jan 4:9:1081940.
doi: 10.3389/fmed.2022.1081940. eCollection 2022.

Managing ulcerative colitis after surgery

Cristina Calvino-Suarez  1 , Rocío Ferreiro-Iglesias  1 , Iria Baston Rey  1 , Manuel Barreiro-de Acosta  1
Affiliations
Review

Managing ulcerative colitis after surgery

Cristina Calvino-Suarez et al. Front Med (Lausanne). .

Abstract

Management of ulcerative colitis after surgery suggested by guidelines (total proctocolectomy with ileal-pouch anal anastomosis) is a big challenge for physicians because patients who believed that their disease had been cured started experiencing very uncomfortable symptoms repeatedly. A high number of patients develop episodes of pouchitis, which is a non-specific inflammation of the pouch whose etiology is unknown. Antibiotics are the elective treatment for acute pouchitis, but regarding chronic pouchitis, this condition is very complicated to treat due to the absence of well-designed specific studies for this group of patients. Antibiotics, budesonide, and biological therapies are some of the recommended drugs for these patients, but despite their use, some need a permanent ileostomy.

Keywords: antibiotics; biologic therapy; colectomy; pouchitis; ulcerative colitis.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Algorithm for the treatment of chronic pouchitis.
See this image and copyright information in PMC

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