A double-peak phenomenon in the pharmacokinetics of veralipride after oral administration: a double-site model for drug absorption
- PMID: 3668801
- DOI: 10.1007/BF01066319
A double-peak phenomenon in the pharmacokinetics of veralipride after oral administration: a double-site model for drug absorption
Abstract
Equal doses of veralipride have been given to 12 healthy volunteers by three different administrations--intravenous infusion, oral solution, and oral capsules--in a randomized cross-over design. After the intake of the solution, but not after infusion or capsules, two maximum plasma concentrations have been observed and interpreted, according to a double-site model for drug absorption.
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