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Review
. 2022 Nov 23:35:58-75.
doi: 10.1016/j.jpra.2022.11.003. eCollection 2023 Mar.

Measurement instruments for the core outcome set of congenital melanocytic naevi and an assessment of the measurement properties according to COSMIN: a systematic review

A C Fledderus  1   2   3 , T Boom  1 , C M Legemate  1 , C M A M van der Horst  1 , P I Spuls  2
Affiliations
Review

Measurement instruments for the core outcome set of congenital melanocytic naevi and an assessment of the measurement properties according to COSMIN: a systematic review

A C Fledderus et al. JPRAS Open. .

Abstract

Background: Congenital melanocytic naevi (CMN) can impact on patients' lives due to their appearance and the risk they carry of neurological complications or melanoma development. The development of a core outcome set (COS) will allow standardised reporting and enable comparison of outcomes. This will help to improve guidelines. In previous research, relevant stakeholders reached a consensus over which core outcomes should be measured in any future care or research. The next step of the COS development is to select the appropriate measurement instruments.

Aim: Step 1: to update a systematic review identifying all core outcomes and measurement instruments available for CMN. Step 2: to evaluate the measurement properties of the instruments for the core outcomes.

Methods: This study was registered in PROSPERO and performed according to the PRISMA checklist. Step 1 includes a literature search in EMBASE (Ovid), PubMed and the Cochrane Library to identify core outcomes and instruments previously used in research of CMN. Step 2 yields a systematic search for studies on the measurement properties of instruments that were either developed or validated for CMN, including a methodological quality assessment following the COSMIN methodology.

Results: Step 1 included twenty-nine studies. Step 2 yielded two studies, investigating two quality of life measurement instruments.

Conclusion: Step 1 provided an overview of outcomes and instruments used for CMN. Step 2 showed that additional research on measurement properties is needed to evaluate which instruments can be used for the COS of CMN. This study informs the instrument selection and/or development of new instruments.

Keywords: Congenital melanocytic naevi (CMN); Core outcome set (COS); Measurement instruments; Measurement properties; Melanoma; Patient reported.

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Conflict of interest statement

The authors have no other financial or personal relationships relevant to this study to disclose.

Figures

Figure 1:
Figure 1
Search 1: Flow diagram.
Figure 2:
Figure 2
Search 2: Flow diagram.
See this image and copyright information in PMC

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References

    1. Koot HM, de Waard-van der Spek F, Peer CD, Mulder PG, Oranje AP. Psychosocial sequelae in 29 children with giant congenital melanocytic naevi. Clin Exp Dermatol. 2000;25(8):589–593. - PubMed
    1. Krengel S, Hauschild A, Schafer T. Melanoma risk in congenital melanocytic naevi: a systematic review. Br J Dermatol. 2006;155(1):1–8. - PubMed
    1. Bittencourt FV, Marghoob AA, Kopf AW, Koenig KL, Bart RS. Large congenital melanocytic nevi and the risk for development of malignant melanoma and neurocutaneous melanocytosis. Pediatrics. 2000;106(4):736–741. - PubMed
    1. Fledderus A, Franke C, Eggen C, van Etten-Jamaludin F, van der Horst C, Brinkmann S, et al. Outcomes and measurement instruments used in Congenital Melanocytic Naevi research: A systematic review. Journal of Plastic, Reconstructive & Aesthetic Surgery. 2019 - PubMed
    1. Oei W, Fledderus AC, Korfage I, Eggen CAM, van der Horst C, Spuls PI, et al. Protocol for the development of core set of domains of the core outcome set for patients with congenital melanocytic naevi (OCOMEN project) Journal of the European Academy of Dermatology and Venereology. 2019 - PubMed

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