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Editorial
. 2023 Apr 3;29(7):1163-1166.
doi: 10.1158/1078-0432.CCR-22-3399.

Much Ado about ASPS: The Rapidly Changing Treatment Paradigms of 2022

Breelyn A Wilky  1 , Alessandra Maleddu  1
Affiliations
Editorial

Much Ado about ASPS: The Rapidly Changing Treatment Paradigms of 2022

Breelyn A Wilky et al. Clin Cancer Res. .

Abstract

A recent randomized phase II study of sunitinib or cediranib in alveolar soft part sarcoma established benchmark activity for commonly used tyrosine kinase inhibitors (TKI). The impact of TKIs, as well as immunotherapy, has redefined treatment paradigms and greatly improved outcomes for this historically dismal sarcoma. See related article by Nguyen et al., p. 1200.

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Comment in

  • Randomized Phase II Trial of Sunitinib or Cediranib in Alveolar Soft Part Sarcoma.
    Nguyen J, Takebe N, Kummar S, Razak A, Chawla SP, George S, Patel SR, Keohan ML, Movva S, O'Sullivan Coyne G, Do K, Juwara L, Augustine B, Steinberg SM, Kuhlmann L, Ivy SP, Doroshow JH, Chen AP. Nguyen J, et al. Clin Cancer Res. 2023 Apr 3;29(7):1200-1208. doi: 10.1158/1078-0432.CCR-22-2145. Clin Cancer Res. 2023. PMID: 36302173 Free PMC article.

Comment on

  • Randomized Phase II Trial of Sunitinib or Cediranib in Alveolar Soft Part Sarcoma.
    Nguyen J, Takebe N, Kummar S, Razak A, Chawla SP, George S, Patel SR, Keohan ML, Movva S, O'Sullivan Coyne G, Do K, Juwara L, Augustine B, Steinberg SM, Kuhlmann L, Ivy SP, Doroshow JH, Chen AP. Nguyen J, et al. Clin Cancer Res. 2023 Apr 3;29(7):1200-1208. doi: 10.1158/1078-0432.CCR-22-2145. Clin Cancer Res. 2023. PMID: 36302173 Free PMC article.

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