Haemorrhoidal disease reduces the risk of diverticular disease and irritable bowel syndrome: a Mendelian randomisation study

Zijun Zhu^#¹, Xinyu Chen^#¹, Chao Wang¹, Sainan Zhang¹, Liang Cheng^{2

3}

Affiliations

¹ College of Bioinformatics and Technology, Harbin Medical University, Harbin, Heilongjiang, China.
² College of Bioinformatics and Technology, Harbin Medical University, Harbin, Heilongjiang, China liangcheng@hrbmu.edu.cn.
³ NHC Key Laboratory of Molecular Probe and Targeted Diagnosis and Therapy, Harbin Medical University, Harbin, Heilongjiang, People's Republic of China.

^# Contributed equally.

PMID: 36693712
DOI: 10.1136/gutjnl-2022-329307

Comment

Haemorrhoidal disease reduces the risk of diverticular disease and irritable bowel syndrome: a Mendelian randomisation study

Zijun Zhu et al. Gut. 2024.

. 2024 Feb 23;73(3):553-554.

doi: 10.1136/gutjnl-2022-329307.

Authors

Zijun Zhu^#¹, Xinyu Chen^#¹, Chao Wang¹, Sainan Zhang¹, Liang Cheng^{2

3}

Affiliations

¹ College of Bioinformatics and Technology, Harbin Medical University, Harbin, Heilongjiang, China.
² College of Bioinformatics and Technology, Harbin Medical University, Harbin, Heilongjiang, China liangcheng@hrbmu.edu.cn.
³ NHC Key Laboratory of Molecular Probe and Targeted Diagnosis and Therapy, Harbin Medical University, Harbin, Heilongjiang, People's Republic of China.

^# Contributed equally.

PMID: 36693712
DOI: 10.1136/gutjnl-2022-329307

No abstract available

Keywords: ANAL; DIVERTICULAR DISEASE.

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Conflict of interest statement

Competing interests: None declared.

Comment in

Mendelian randomisation shows diverticular disease and irritable bowel syndrome increase the risk of haemorrhoidal disease.
Juzenas S, Ellinghaus D, Sanna S, Franke A, D'Amato M. Juzenas S, et al. Gut. 2024 Jul 11;73(8):1403-1404. doi: 10.1136/gutjnl-2023-330364. Gut. 2024. PMID: 37813565 Free PMC article. No abstract available.

Comment on

Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.
Zheng T, Ellinghaus D, Juzenas S, Cossais F, Burmeister G, Mayr G, Jørgensen IF, Teder-Laving M, Skogholt AH, Chen S, Strege PR, Ito G, Banasik K, Becker T, Bokelmann F, Brunak S, Buch S, Clausnitzer H, Datz C; DBDS Consortium; Degenhardt F, Doniec M, Erikstrup C, Esko T, Forster M, Frey N, Fritsche LG, Gabrielsen ME, Gräßle T, Gsur A, Gross J, Hampe J, Hendricks A, Hinz S, Hveem K, Jongen J, Junker R, Karlsen TH, Hemmrich-Stanisak G, Kruis W, Kupcinskas J, Laubert T, Rosenstiel PC, Röcken C, Laudes M, Leendertz FH, Lieb W, Limperger V, Margetis N, Mätz-Rensing K, Németh CG, Ness-Jensen E, Nowak-Göttl U, Pandit A, Pedersen OB, Peleikis HG, Peuker K, Rodriguez CL, Rühlemann MC, Schniewind B, Schulzky M, Skieceviciene J, Tepel J, Thomas L, Uellendahl-Werth F, Ullum H, Vogel I, Volzke H, von Fersen L, von Schönfels W, Vanderwerff B, Wilking J, Wittig M, Zeissig S, Zobel M, Zawistowski M, Vacic V, Sazonova O, Noblin ES; 23andMe Research Team; Farrugia G, Beyder A, Wedel T, Kahlke V, Schafmayer C, D'Amato M, Franke A. Zheng T, et al. Gut. 2021 Apr 22;70(8):1538-49. doi: 10.1136/gutjnl-2020-323868. Online ahead of print. Gut. 2021. PMID: 33888516 Free PMC article.

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Haemorrhoidal disease reduces the risk of diverticular disease and irritable bowel syndrome: a Mendelian randomisation study

Affiliations

Haemorrhoidal disease reduces the risk of diverticular disease and irritable bowel syndrome: a Mendelian randomisation study

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