Days and weeks do matter: a call for testing infants at risk of HIV acquisition at birth

Hermione Lyall¹, Hélène Côté^{1

2}, Patricia M Flynn³

Affiliations

¹ Department of Paediatrics, Imperial College Healthcare NHS Trust, London, UK.
² Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, Canada.
³ Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.

Comment

Hermione Lyall et al. AIDS. 2023.

. 2023 Mar 1;37(3):545-546.

doi: 10.1097/QAD.0000000000003468.

Hermione Lyall¹, Hélène Côté^{1

2}, Patricia M Flynn³

¹ Department of Paediatrics, Imperial College Healthcare NHS Trust, London, UK.
² Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, Canada.
³ Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.

No abstract available

Comment on

Hospitalization among infants who initiate antiretroviral therapy before 3 months of age.
Anderson K, Iyun V, Eley BS, Rabie H, Ferreira T, Nuttall J, Frigati L, Van Dongen N, Davies MA; IeDEA-SA. Anderson K, et al. AIDS. 2023 Mar 1;37(3):435-445. doi: 10.1097/QAD.0000000000003422. Epub 2022 Nov 10. AIDS. 2023. PMID: 36695356 Free PMC article.

1. Cotton MF, Violari A, Otwombe K, Panchia R, Dobbels E, Rabie H, et al. Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial . Lancet 2013; 382:1555–1563.
1. Anderson K, Iyun V, Eley BS, Rabie H, Ferreira T, Nuttall J, et al. Hospitalization among infants who initiate antiretroviral therapy before 3 months of age . AIDS 2023; 37:435–445.
1. World Health Organization. Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach. July 2021. Available at: https://www.who.int/publications/i/item/9789240031593 [cited 2022 Nov 28].
1. Tagarro A, Chan M, Zangari P, Ferns B, Foster C, De Rossi A, et al. Early and highly suppressive antiretroviral therapy are main factors associated with low viral reservoir in European perinatally HIV-infected children . J Acquir Immune Defic Syndr 2018; 79:269–276.
1. Persaud D, Gay H, Ziemniak C, Chen YH, Piatak M Jr, Chun TW, et al. Absence of detectable HIV-1 viremia after treatment cessation in an infant . N Engl J Med 2013; 369:1828–1835.