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Review
. 2023 Apr;20(2):100-110.
doi: 10.1007/s11904-023-00645-1. Epub 2023 Jan 25.

Updates on HIV and Kidney Disease

C Elena Cervantes  1 , Mohamed G Atta  2
Affiliations
Review

Updates on HIV and Kidney Disease

C Elena Cervantes et al. Curr HIV/AIDS Rep. 2023 Apr.

Abstract

Purpose of review: With the advent of antiretroviral therapy, HIV infection has become a chronic disease in developed countries.

Recent findings: Non-HIV-driven risk factors for kidney disease, such as APOL1 risk variants and other genetic and environmental factors, have been discovered and are better described. Consequently, the field of HIV-associated kidney disease has evolved with greater attention given to traditional risk factors of CKD and antiretroviral treatment's nephrotoxicity. In this review, we explore risk factors of HIV-associated kidney disease, diagnostic tools, kidney pathology in HIV-positive individuals, and antiretroviral therapy-associated nephrotoxicity.

Keywords: Antiretroviral therapy; HIV-associated kidney disease; HIVAN; Immune complex kidney disease in the setting of HIV; Interstitial nephritis.

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