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Comment
. 2023 Jan 25;21(1):e3001998.
doi: 10.1371/journal.pbio.3001998. eCollection 2023 Jan.

The dawn of relaxed phylogenetics

Affiliations
Comment

The dawn of relaxed phylogenetics

Jacob L Steenwyk et al. PLoS Biol. .

Abstract

Tracing the history of evolution across time is a primary goal of evolutionary biology. The 2006 publication of a landmark study on relaxed phylogenetics in PLOS Biology enabled biologists to shed light on evolution's tempo and shaped the future of evolutionary studies.

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Conflict of interest statement

I have read the journal’s policy and the authors of this manuscript have the following competing interests: JLS is a scientific consultant for Latch AI Inc. JLS is a scientific advisor for WittGen Biotechnologies. AR is a scientific consultant for LifeMine Therapeutics, Inc.

Figures

Fig 1
Fig 1. Cartoon representations of different clock models.
Global clocks impose the same substitution rate across the phylogeny. Local clocks use the same substitution rate for user-defined lineages. Autocorrelated clocks assume that substitution rates gradually change across speciation events resulting in closely related lineages having similar rates. In relaxed clocks—the critical component of relaxed phylogenetics—the substitution rate of each branch is independent of other branches.

Comment on

References

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