Improvement of stress adaptation and insulin resistance in women with GDM by WeChat group management during novel coronavirus pneumonia

Abstract

Aim: To evaluate the improvement of glycemic control and stress adaptation in patients with GDM by mobile phone WeChat management during novel coronavirus pneumonia.

Methods: In this study, 75 women with GDM were included, of whom 35 were included in mobile WeChat group management as the GDM-M group and 40 as the GDM group.

Results: After mobile WeChat group management for 4 weeks, E and NE were lower. MDA was lower, and SOD was higher. HOMA-IR was lower. E, NE, and cortisol were related to HOMA-IR positively, MDA was positively related to HOMA-IR, and SOD was negatively related to HOMA-IR. E and cortisol were positively related to MDA but negatively related to SOD.

Conclusion: The stress adaptation disorder and insulin resistance in patients with GDM who have completed mobile WeChat group management can be improved during novel coronavirus pneumonia. Mobile WeChat management played a positive role in improving the insulin resistance of women with GDM under special circumstances, which may reduce the risk of maternal and fetal complications.

Keywords: GDM; insulin resistance; mobile phone management; novel coronavirus pneumonia (COVID-19); stress adaptation.

Figure 1

Histograms of plasma stress, oxidative stress, and glucose-related indexes—cortisol (A), E (B), NE (C), MDA (D), SOD (E), and HOMA-IR (F) in two groups. Data are presented as mean ± SD. A two-sample t-test was used to determine whether the differences in the GDM-M group were statistically significant. *Indicates P < 0.05 vs. GDM group, and P < 0.01 is expressed by**. E, epinephrine; NE, noradrenaline; MDA, malondialdehyde; SOD, superoxide dismutase.