Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022;14(4):234-239.
doi: 10.34172/jcvtr.2022.30520. Epub 2022 Dec 17.

The correlation between speckle-tracking echocardiography and coronary angiography in suspected coronary artery disease with normal left ventricular function

Krishan Yadav  1 , Jayesh Prajapati  2 , Gaurav Singh  2 , Iva Patel  3 , Ajay Karre  2 , Pradeep Kumar Bansal  2 , Vicky Garhwal  2
Affiliations

The correlation between speckle-tracking echocardiography and coronary angiography in suspected coronary artery disease with normal left ventricular function

Krishan Yadav et al. J Cardiovasc Thorac Res. 2022.

Abstract

Introduction: Our study objects to determine the diagnostic accuracy of two-dimensional speckle tracking echocardiography (2DSTE) in predicting presence and severity of coronary artery disease (CAD). Methods: Patients with stable angina pectoris with normal left ventricular function (>50%) undergoing coronary angiography were enrolled and subjected to speckle tracking echocardiography. Global longitudinal peak systolic strain was measured and correlated to the results of coronary angiography for each patient. Results: Number of male (P=0.001), diabetes (P=0.01) and smoking (P=0.01) patients were significantly higher in the CAD group compared to non-CAD patients. Global longitudinal peak systolic strain (GLPSS) was significantly (P=0.0001) lower in CAD patients in comparison to non- CAD patients. GLPSS showed significantly lower in patients with Syntax score (SS)≥22 in comparison to SS<22. Cut-off value -19 for GLPSS could be used to predict the presence of significant CAD with 80.6% sensitivity and 76.5% specificity (area under curve (AUC) -0.83, P=0.0001). The mean GLPSS value decreased as the number of diseased coronary vessels increased (P=0.0001). The optimal cut-off value of -16 GLPSS with a sensitivity of 76.7% and specificity of 83.3% [AUC 0.84, P<0.0001] was found significant to predict CAD severity. Multivariate regression of GLPSS and another risk factor for predicting significant CAD, GLPSS showed OR=1.55 (CI-1.36-1.76) P=0.0001 for predicting the presence of CAD. Conclusion: 2DSTE can be used as a non-invasive screening test in predicting presence, extent and severity of significant CAD patients with suspected stable angina pectoris.

Keywords: Global Longitudinal Peak Systolic Strain; Speckle Tracking Echocardiography; Suspected Stable Angina Pectoris.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Figure 2
Figure 2
Figure 3
Figure 3
Figure 4
Figure 4
Figure 5
Figure 5
See this image and copyright information in PMC

References

    1. Gupta R. Recent trends in coronary heart disease epidemiology in India. Indian Heart J. 2008;60(2 Suppl B):B4–18. - PubMed
    1. Skelly AC, Hashimoto R, Buckley DI, Brodt ED, Noelck N, Totten AM, et al. Noninvasive Testing for Coronary Artery Disease. Rockville, MD: Agency for Healthcare Research and Quality (US); 2016. - PubMed
    1. Heo R, Nakazato R, Kalra D, Min JK. Noninvasive imaging in coronary artery disease. Semin Nucl Med. 2014;44(5):398–409. doi: 10.1053/j.semnuclmed.2014.05.004. - DOI - PMC - PubMed
    1. Tsai WC, Liu YW, Huang YY, Lin CC, Lee CH, Tsai LM. Diagnostic value of segmental longitudinal strain by automated function imaging in coronary artery disease without left ventricular dysfunction. J Am Soc Echocardiogr. 2010;23(11):1183–9. doi: 10.1016/j.echo.2010.08.011. - DOI - PubMed
    1. Hoit BD. Strain and strain rate echocardiography and coronary artery disease. Circ Cardiovasc Imaging. 2011;4(2):179–90. doi: 10.1161/circimaging.110.959817. - DOI - PubMed

LinkOut - more resources