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Case Reports
. 2023 Jan 20;102(3):e32654.
doi: 10.1097/MD.0000000000032654.

Occult colon cancer with liver abscess and pancreatitis as the first manifestations: A case report

Shan Yang  1 , Jin Zhao, Qi Liu
Affiliations
Case Reports

Occult colon cancer with liver abscess and pancreatitis as the first manifestations: A case report

Shan Yang et al. Medicine (Baltimore). .

Abstract

Introduction: Klebsiella pneumoniae-induced liver abscess (KP-PLA) is a common type of pyogenic liver abscess, severe acute pancreatitis (SAP) has high mortality, and poor prognosis in advanced colon cancer. There have been no report of SAP complicated with colon cancer after KP-PLA as so far. In this study, we reported a case of SAP secondary to KP-PLA with colon cancer for the first time, so as to provide reference for clinical diagnosis and treatment of these diseases.

Patient concerns and diagnosis: A 64-year-old woman with a history of diabetes visited our hospital with abdominal pain for 5 + days. He was diagnosed with KP-PLA a month ago, which had not healed when he was admitted. He was diagnosed with SAP, and histological examination of colonic biopsy confirmed the diagnosis of moderately differentiated adenocarcinoma.

Interventions and outcomes: He was treated with intravenous antibiotics and underwent modified endoscopic mucosal resection under colonoscopy. We conducted a 2-month follow-up, and there was no recurrence of liver abscess and pancreatitis.

Conclusion: Screening for intestinal tumors is necessary in patients with cryptogenic liver abscess, especially KP-PLA with diabetes.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
Abscess formed in S6 segment of liver.
Figure 2.
Figure 2.
Acute pancreatitis with peripancreatic exudation and pancreatic cyst formation.
Figure 3.
Figure 3.
(A) Electronic colonoscopy of sigmoid mass, appearance of vegetable; (B) The measured size of the mass was about 3.5cm × 2.5 cm × 1.7 cm.
Figure 4.
Figure 4.
(A) The tumors were glandular in arrangement under microscope, and some cells had atypia (HE, ×40). (B) Desmin staining +. (C) Ki-67 < 30%.
Figure 5.
Figure 5.
The whole diagnosis, treatment, and prognosis of this case.
See this image and copyright information in PMC

References

    1. Yin D, Changyong J, Zhang S, et al. . Clinical characteristics and management of 1572 patients with pyogenic liver abscess: A 12-year retrospective study. Liver Int. 2021;41:810–8. - PMC - PubMed
    1. Liu YC, Cheng DL, Lin CL. Klebsiella pneumoniae liver abscess associated with septic endophthalmitis. Arch Intern Med. 1986;146:1913–16. - PubMed
    1. Sun R, Zhang H, Yingchun X, et al. . Klebsiella pneumoniae-related invasive liver abscess syndrome complicated by purulent meningitis: a review of the literature and description of three cases. BMC Infect Dis. 2021;21:15. - PMC - PubMed
    1. Zhang C-G, Wang Y, Duan M, et al. . Klebsiella pneumoniae invasion syndrome: a case of liver abscess combined with lung abscess, endophthalmitis, and brain abscess. J Int Med Res. 2022;50:3000605221084881. - PMC - PubMed
    1. Al Kaabi S, Al Kaabi A, Al Nuaimi H. What is beyond Salmonella gastroenteritis? A case of acute pancreatitis complicating Salmonella infection in a child: a case report and literature review. BMC Pediatr. 2021;21:353. - PMC - PubMed

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