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Review
. 2023 Mar;119(3):348-354.
doi: 10.1016/j.fertnstert.2023.01.031. Epub 2023 Jan 23.

Racial and ethnic disparities in polycystic ovary syndrome

Katherine VanHise  1 , Erica T Wang  1 , Keith Norris  2 , Ricardo Azziz  3 , Margareta D Pisarska  1 , Jessica L Chan  4
Affiliations
Review

Racial and ethnic disparities in polycystic ovary syndrome

Katherine VanHise et al. Fertil Steril. 2023 Mar.

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine disorder that impacts women worldwide. There are several racial and ethnic differences in PCOS phenotypes and in PCOS- associated metabolic dysfunction. In this review, we summarize the current literature on disparities in the diagnosis and outcomes associated with PCOS in the United States. Future studies are needed to address gaps in knowledge for racial and ethnic-specific differences in PCOS, and include a large number of non-White and/or Hispanic participants in PCOS studies.

Keywords: PCOS; disparities; ethnicity; polycystic ovary syndrome; race.

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Figures

FIGURE 1
FIGURE 1
A summary of racial and ethnic disparities in women with PCOS in the United States. HOMA-IR = homeostatic model assessment of insulin resistance; SBP = systolic blood pressure; DBP = diastolic blood pressure; GTT = glucose tolerance test; TC = total cholesterol; HDL = high-density lipoprotein; LDL = low-density lipoprotein; TG = triglycerides; PCOS = polycystic ovary syndrome. VanHise. Racial and ethnic disparities in PCOS. Fertil Steril 2023.
See this image and copyright information in PMC

References

    1. Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, et al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril 2018;110:364–79. - PMC - PubMed
    1. Vink JM, Sadrzadeh S, Lambalk CB, Boomsma DI. Heritability of polycystic ovary syndrome in a Dutch twin-family study. J Clin Endocrinol Metab 2006;91:2100–4. - PubMed
    1. Hiam D, Moreno-Asso A, Teede HJ, Laven JSE, Stepto NK, Moran LJ, et al. The genetics of polycystic ovary syndrome: an overview of candidate gene systematic reviews and genome- wide association studies. J Clin Med 2019;8. - PMC - PubMed
    1. Chen ZJ, Zhao H, He L, Shi Y, Qin Y, Shi Y, et al. Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat Genet 2011;43:55–9. - PubMed
    1. Goodarzi MO, Jones MR, Li X, Chua AK, Garcia OA, Chen YD, et al. Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts. J Med Genet 2012;49:90–5. - PMC - PubMed

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