Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep 29;38(10):2152-2159.
doi: 10.1093/ndt/gfad021.

High rates of psychological distress, mental health diagnoses and suicide attempts in people with chronic kidney disease in Ireland

Affiliations

High rates of psychological distress, mental health diagnoses and suicide attempts in people with chronic kidney disease in Ireland

Clodagh Cogley et al. Nephrol Dial Transplant. .

Abstract

Background: People with chronic kidney disease (CKD) experience high levels of psychological distress, which is associated with higher mortality and adverse health outcomes. Little is known about the rates of a range of mental health difficulties or rates of suicide attempts in people with CKD.

Methods: Individuals with CKD (n = 268; age range 18-94 years, mean = 49.96 years) on haemodialysis (n = 79), peritoneal dialysis (n = 46), transplant recipients (n = 84) and who were not on renal replacement therapy (RRT; n = 59) were recruited through the Irish Kidney Association social media pages and three Irish hospitals. Participants completed surveys to gather demographics and mental health histories, the Hospital Anxiety and Depression Scale (HADS) and the 12-item Short Form Health Survey (SF-12) to measure health-related quality of life (HRQoL).

Results: A total of 23.5% of participants self-reported they had received a mental health diagnosis, with depression (14.5%) and anxiety (14.2%) being the most common, while 26.4% of participants had experienced suicidal ideation and 9.3% had attempted suicide. Using a clinical cut-off ≥8 on the HADS subscales, current levels of clinically significant anxiety and depression were 50.7% and 35.4%, respectively. Depression levels were slightly higher for those on haemodialysis compared with those with a transplant and those not on RRT. Depression, anxiety and having a mental health diagnosis were all associated with lower HRQoL.

Conclusions: People with CKD in Ireland experience high levels of psychological distress, mental health difficulties, suicidal ideation and suicide attempts. The identification of and intervention for mental health difficulties in CKD should be prioritised in clinical care.

Keywords: kidney disease; kidney failure; mental health; psychological distress; suicide.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Graphical Abstract
Graphical Abstract
Figure 1:
Figure 1:
Mean anxiety level by RRT modality. HD: haemodialysis; PD: peritoneal dialysis; RRT: renal replacement therapy.
Figure 2:
Figure 2:
Mean depression level by RRT modality. HD: haemodialysis; PD: peritoneal dialysis; RRT: renal replacement therapy.

Similar articles

Cited by

References

    1. Huang CW, Wee PH, Low LLet al. . Prevalence and risk factors for elevated anxiety symptoms and anxiety disorders in chronic kidney disease: a systematic review and meta-analysis. Gen Hosp Psychiatry 2021;69:27–40. 10.1016/j.genhosppsych.2020.12.003 - DOI - PubMed
    1. Seery C, Buchanan S. The psychosocial needs of patients who have chronic kidney disease without kidney replacement therapy: a thematic synthesis of seven qualitative studies. J Nephrol 2022;35:2251–67. 10.1007/s40620-022-01437-3 - DOI - PMC - PubMed
    1. Schouten RW, Haverkamp GL, Loosman WLet al. . Anxiety symptoms, mortality, and hospitalization in patients receiving maintenance dialysis: a cohort study. Am J Kidney Dis 2019;74:158–66. 10.1053/j.ajkd.2019.02.017 - DOI - PubMed
    1. Loosman WL, Rottier MA, Honig Aet al. . Association of depressive and anxiety symptoms with adverse events in Dutch chronic kidney disease patients: a prospective cohort study. BMC Nephrol 2015;16:155. 10.1186/s12882-015-0149-7 - DOI - PMC - PubMed
    1. Palmer SC, Vecchio M, Craig JCet al. . Association between depression and death in people with CKD: a meta-analysis of cohort studies. Am J Kidney Dis 2013;62:493–505. 10.1053/j.ajkd.2013.02.369 - DOI - PubMed

Publication types