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Case Reports
. 2023 Mar;29(3):647-649.
doi: 10.3201/eid2903.221845. Epub 2023 Jan 26.

Sustained Mpox Proctitis with Primary Syphilis and HIV Seroconversion, Australia

Rachel M Burdon, David Atefi, Jainoor Rana, Arun Parasuraman, Andie S Lee, Blake Nield
Case Reports

Sustained Mpox Proctitis with Primary Syphilis and HIV Seroconversion, Australia

Rachel M Burdon et al. Emerg Infect Dis. 2023 Mar.

Abstract

A 26-year-old man in Australia who has sex with men had severe perianal ulceration, proctitis, and skin lesions develop. Testing revealed primary syphilis, mpox, and primary HIV infection. Recent publications have documented severe mpox associated with HIV infection. Disruption of mucosal integrity by mpox lesions could enable HIV transmission and vice versa.

Keywords: Australia; HIV/AIDS; Monkeypox virus; acute HIV seroconversion; monkeypox; mpox; proctitis; sexually transmitted infections; syphilis; viruses.

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Figures

Figure
Figure
Timeline of symptom development and infectious vector incubation periods in case of patient with sustained mpox proctitis with primary syphilis and HIV seroconversion, Australia
See this image and copyright information in PMC

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Supplementary concepts