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Review
. 2023 Jan 10:9:1068681.
doi: 10.3389/fsurg.2022.1068681. eCollection 2022.

Effect of bariatric surgery on carotid intima-media thickness: A meta-analysis based on observational studies

Hui Zhou  1 , Yangli Jin  2 , Senjie Dai  3 , Chenglong Dai  4 , Xia Ye  5
Affiliations
Review

Effect of bariatric surgery on carotid intima-media thickness: A meta-analysis based on observational studies

Hui Zhou et al. Front Surg. .

Abstract

Objective: This meta-analysis aimed to investigate the effect of bariatric surgery on CIMT in people with obesity.

Methods: PubMed, Web of Science, Embase, and the Cochrane Library were searched for observational studies assessing the effect of bariatric surgery on CIMT from inception to August 2022. Mean difference (MD) and 95% confidence intervals were calculated to assess CIMT.

Results: A total of 23 studies, including 1,349 participants, were eligible to participate in this meta-analysis. The results revealed that CIMT was significantly decreased at 6 months, 12 months, and more than 18 months after bariatric surgery compared with baseline (6 months: MD = 0.09; P < 0.01; 12 months: MD = 0.12; P < 0.01; more than 18 months: MD = 0.14; P = 0.02). Meanwhile, laparoscopic Roux-en-Y gastric bypass (LRYGB) seemed to be more effective than laparoscopic sleeve gastrectomy (LSG) in lowering CIMT in terms of the type of surgery (LSG: MD = 0.11; P < 0.01; LRYGB: MD = 0.14; P < 0.01). Lastly, the benefits of bariatric surgery on CIMT was independent of gender (Male: MD = 0.06; P = 0.04; Female: MD = 0.08; P = 0.03).

Conclusions: Bariatric surgery is consistently effective in reducing CIMT in people with obesity.

Keywords: bariatric surgery; carotid intima-Media thickness; meta-analysis; obesity; weight loss.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Flow chart for the selection of studies included in the meta-analysis.
Figure 2
Figure 2
Forest plot of meta-analysis of CIMT at 6 months after bariatric surgery. (Cobeta 2020 and Solmaz 2016 respectively included two subsets of data for meta-analysis).
Figure 3
Figure 3
Forest plot of meta-analysis of CIMT at 12 months after bariatric surgery. (Gómez-Martin 2020 included two subsets of data for meta-analysis).
Figure 4
Figure 4
Forest plot of meta-analysis of CIMT more than 18 months after bariatric surgery.
Figure 5
Figure 5
Forest plot of meta-analysis for CIMT by the type of surgery. (Cobeta 2020, Garcia 2013, Habib 2009, Gómez-Martin 2020 respectively included two subsets of data for meta-analysis).
Figure 6
Figure 6
Forest plot of meta-analysis for CIMT by gender. (Cobeta 2020 and Gomez-Martin 2020 respectively included two subsets of data for meta-analysis).
See this image and copyright information in PMC

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