Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Dec 31;36(4):294-297.
doi: 10.4285/kjt.22.0016. Epub 2022 Nov 23.

The first successful report of liver transplantation from category III donation after circulatory death in South Korea: a case report

Incheon Kang  1 , Jae-Myeong Lee  2 , Jae Geun Lee  3
Affiliations
Case Reports

The first successful report of liver transplantation from category III donation after circulatory death in South Korea: a case report

Incheon Kang et al. Korean J Transplant. .

Abstract

Deceased donor liver transplantation (DDLT) using donations after brain death (DBDs) has been widely performed in Korea. However, to date, there is no report regarding donation after circulatory death (DCD) category III. A 56-year-old male patient diagnosed with hepatitis B virus-associated liver cirrhosis underwent DDLT using DCD category III. The recipient's recovery was uneventful, and he was discharged on postoperative day 37. Currently, the patient is alive, with no complications 20 months after transplantation. This case suggests that DCD with LT is both feasible and safe. Further studies are required to validate this finding.

Keywords: Case report; Graft survival; Liver transplantation; Tissue and organ procurement; Warm ischemia.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Timeline of donation after circulatory death organ procurement. SpO2, peripheral oxygen saturation.
Fig. 2
Fig. 2
Preoperative imaging. Pretransplant computed tomography revealed overt liver cirrhosis with a large amount of ascites. (A) Axial view. (B) Coronal view.
Fig. 3
Fig. 3
Postoperative imaging. (A) Computed tomography (CT) performed 2 weeks after transplantation showed no significant abnormal findings. (B) CT performed 18 months after transplantation also showed no abnormal findings.
See this image and copyright information in PMC

References

    1. Bohorquez H, Seal JB, Cohen AJ, Kressel A, Bugeaud E, Bruce DS, et al. Safety and outcomes in 100 consecutive donation after circulatory death liver transplants using a protocol that includes thrombolytic therapy. Am J Transplant. 2017;17:2155–64. doi: 10.1111/ajt.14261. - DOI - PubMed
    1. Jeong E, Oh J, Lee Y, Lee J. The first donation after circulatory death following withdrawal of life-sustaining treatment in Korea. Korean J Transplant. 2020;34(Suppl 1):S30. doi: 10.4285/ATW2020.OR-1066. - DOI
    1. Kang I, Lee JG, Choi SH, Kim HJ, Han DH, Choi GH, et al. Impact of everolimus on survival after liver transplantation for hepatocellular carcinoma. Clin Mol Hepatol. 2021;27:589–602. doi: 10.3350/cmh.2021.0038. - DOI - PMC - PubMed
    1. Choi HJ. Current status and outcome of liver transplantation in South Korea. Clin Mol Hepatol. 2022;28:117–9. doi: 10.3350/cmh.2021.0381. - DOI - PMC - PubMed
    1. Goldaracena N, Cullen JM, Kim DS, Ekser B, Halazun KJ. Expanding the donor pool for liver transplantation with marginal donors. Int J Surg. 2020;82 Suppl:30–5. doi: 10.1016/j.ijsu.2020.05.024. - DOI - PubMed

Publication types

LinkOut - more resources